Acne
Acne is an inflammatory skin disorder characterized by pimples, blackheads, and white heads.
To some point it affects about 80% of all Americans between the ages of twelve and forty-four. Acne has become the most commonly treated skin condition. Possibly western lifestyle contributes to this change. The contributing factors include stress, diet, allergy, air contamination and many other environmental factors.
Acne often arises in puberty, when a body severely increases its production of male sex hormones. Acne is not just affecting kids anymore - it is also affecting increasing number of adults. Many women suffer premenstrual acne flare-ups prompted by the release of progesterone after ovulation. Factors that can contribute to this problem include heredity, oily skin, hormonal imbalance, and candidiasis. A body pH that is too acidic or too alkaline also fosters the nesting of acne-causing bacteria.
Natural approach:
~ Acidophilus (by Renew Life) replenishes essential bacteria to reduce outbreaks.
~ Colloidal Silver (by Sovereign Silver) acts as a natural antibiotic
~ Essential Fatty acids (by The Natural Way) provide essential gamma-lanolenic acid to keep skin smooth and soft, repair tissue and dissolve fatty deposits that block pores.
Also aids in healing:
~ Good source of multivitamins as A, B, C, D3, E and Zinc (by The Natural Way, Garden of Life, New Chapter…etc) act as antioxidants, antistressors, improve blood flow, promote immune function and reduce inflammation.
Herbs:
~ Burdock root, dandelion, milk thistle, and a red clover are good to combat acne.
~ Lavender and strawberry leaves can be used in steam sauna for the face.
~ Tee Tree Oil, a natural antibiotic and antiseptic, could be applied a few times a day directly to blemishes, but be careful if a rush appears and discontinue full strength and use diluted.
Adrenal Disorders
Dysfunctions that are directly related to the adrenal gland include reduced adrenal function, usually referred to as low adrenal reserve.
The adrenal glands produce enough hormones to maintain a relatively normal state of health but stressful situations increase the need for hormones that malfunctioning adrenals cannot produce leading to anything from fatigue to total collapse. Symptoms of reduces adrenal function can include weakness, lethargy, fatigue, recurrent infections, dizziness, low blood pressure when first standing, headaches, memory problems, food craving, allergies and blood sugar disorders.
Natural Approach:
~ Vitamin B complex (by The Natural Way, Solaray, New Chapter, garden of Life, etc.) necessary for adrenal function.
~ Vitamin C with bioflavonoids (by The Natural Way, Solaray, Nature's Plus, etc.) vital for proper functioning of adrenal glands.
~ L-Tyrosine 500 mg. (by Solaray, Now, Natural Factors etc.) aids adrenal glands function relieves excess stress put on glands. Caution: Do not take tyrosine if you taking MAO inhibitors drugs.
~ Raw Adrenal glandular protein derived from this product helps to rebuild and repair the adrenal glands.
~ Coenzyme Q10 (by The Natural Way, Natural Factors, Solgar, Now, etc.) carries oxygen to all glands.
~ High-Potency Multivitamins (by The Natural Way, Solaray, New Chapter, Garden of Life, Enzymatic Therapy) all nutrients are needed to support proper adrenal function.
Herbs:
~ Milk Thistle aids liver function, which in turn helps adrenal function.
~ Herbs such as Kava-Kava, St.Johns wort, Valerian root are good stress reducers.
~ Siberian ginseng and Ashwagandha are also known as adaptogen and helping cope with stressful situation. Caution: Do not take ginseng if you have hypoglycemia, high blood pressure, or a heart problem.
Aging
Aging is not an illness or disorder but it does make our bodies more susceptible to various diseases. There are many theories on aging and its causes. Some of the more well-known ones are:
DNA/genetic theory - Things that happened in our lifespan can damage the DNA and they include: exposure to pollutants, toxins, radiation, our diet and many other environmental factors.
Neuroendocrine theory - Secretion of hormones gradually decreases over time.
Free radical/oxidation theory - environmental factors, exposure to toxins, pollutants, radiation, alcohol, tobacco as well as diet, cause highly reactive cell by-products called free radicals.
Immune theory - the immune system gradually gets less effective as we age.
Telomere theory - Cells in the body are replaced by means of cell division, and there is a limit on the number of times they may divide successfully.
Stem cell theory - this theory explains that as we age we begin loosing stem cells from the reserve we are granted at birth.
Adding the right supplement should give you the power needed to boost your immunity, and prevent most disorders. Looking youthful for your age is an added bonus.
Natural approach:
~ Alfa-lipoic acid (by The Natural Way, Solaray, Solgar etc.) powerful antioxidant, an aids proper sugar balance.
~ Coenzyme Q10 (by The Natural Way, Solgar, Natural Factors, etc) aids circulation, improves cellular oxygenation, protects the heart.
~ Multivitamins and mineral complex with natural beta carotene (by The Natural Way, Solaray, etc) - high quality vitamins, guard all organs including lungs.
~ Omega3 essential fatty acids (by The Natural Way, Nordic, Barlean's) plays an important role in cell formation, essential for proper brain function, protects heart and keep vessels from formation of plaque.
~ A group of amino acids such as L-arginine, L-carnitine, L-lysine, L-methionine,
L-ornithine, L-tyrosine, N-acetylcystine.
~ 5- HTP (by The Natural way, Solaray, Now, Natural Factors, etc) - an important neurotransmitter.
~ Lecithin granules or capsules - improves memory and brain function. A fat emulsifier.
~ Phosphatidyl serine (by The Natural way, Solgar, etc) - improves brain function.
~ RNA and DNA - excellent for healthy cell reproduction. Caution: do not take if you have gout.
Herbs:
~ Green tea - aids in cancer avoidance.
~ Noni - relieve joint problem, support cellular regeneration, and improve digestion.
~ Kava-Kava, St. John's wort, Valerian - is valuable as sleep aid, and tranquilizers.
~ Saw Palmetto - for men and Wild yam for women - regulate sexual hormone production.
~ Nettle - full of vital minerals and is good for depression, allergies, hypoglycemia, prostate and urinary tract disorders.
Please visit one of our stores and our knowledgeable personnel will help you choose the right product and answer all your questions.
Allergies
An allergic reaction is an inappropriate immune reaction to an otherwise harmless substance. Allergens can be environmental, chemical, or food-based. Common allergens include dust mites, pollen, animal dander, and certain foods. Allergens can be absorbed into the body through the skin, respiratory tract, or gastrointestinal tract. Allergens are proteins or low-molecular weight substances that the body identifies as antigenic. This creates an immune response known as a hypersensitive or allergic reaction. The production of chemical mediators in these allergic reactions may produce symptoms ranging from mild to life threatening.
Under normal conditions, the immune system is highly adept at recognizing and destroying the myriad of foreign substances capable of invading the body (i.e., bacteria, viruses, parasites). The complex mechanisms of immune defense usually work in tandem with the host tissues of the body, averting secondary damage and destruction. The immune system consists of several branches, each with its own protective functions. B-lymphocytes (B cells) and plasma cells produce a series of plasma proteins known as immunoglobulins. Immunoglobulins are antibodies capable of recognizing, destroying, and positioning antigens for removal from the body.
The etiology of allergic reactions is unclear. Some immunologists suggest that allergic reactions stem from an evolutionary response to parasitic infection. This theory proposes that the human immune system has developed a high sensitivity to parasites, which increase white blood cell production, and the release of pro-inflammatory factors. In developed countries, where parasitic infestation is relatively low, allergies are more common than in less developed countries. It is thought that when the immune system is fighting parasitic infections, it does not have the resources to defend against less threatening agents. Another theory is that people with dysbiosis may have a heightened allergic response.
Statistics
Centers for Disease Control (CDC), 2008
- Food allergies in the U.S. affect approximately 3 million children. An 18 percent increase since 1997.
World Health Organization, 2005.
- Allergic rhinoconjunctivitis affects more than 115 million people worldwide.
- 30%-50% of people are genetically predisposed to develop Immunoglobulin E antibody (IgE) to common environmental allergens.
Centers for Disease Control, 2004.
- 12% of U.S. children under 18 years of age suffered from respiratory allergies in the past 12 months.
- Children living in the South (15%) were more likely to have respiratory allergies than those living in the Midwest (11%), Northeast (10%), or West (8%).
American Academy of Allergy, Asthma and Immunology in San Diego, 1999.
- 50 million people suffer from allergies.
- Of these, 1/6 have allergic asthma.
- 6 million have non allergic asthma caused by exercise, chemical pollution, and smoking.
Natural Approach
In the 1940s, it was first discovered that vitamin C was useful in the treatment of allergies. In a chronic allergies study, 10 men and women participated for 6 weeks ingesting a placebo for 4 weeks and 2g/day of vitamin C for 2 weeks. There was a significant rise in plasma ascorbate and a decrease in histamine levels of 38% after vitamin C supplementation indicating that vitamin C’s usefulness in allergy treatment may stem from the fact that it metabolizes, or detoxifies, histamine in vivo. Another study demonstrated that 11 people who had either low vitamin C levels or elevated blood histamine levels, given 1 gm of vitamin C daily for three days, had their blood histamine levels decline. A two week randomized study involving 60 patients suffering from perennial allergic rhinitis were administered a solution of ascorbic acid. The solution caused a decrease in symptoms in 74 percent of patients.
This agent has been reported to reduce allergic reactions by inhibiting the release of histamine from mast cells. Quercetin belongs to a class of compounds known as bioflavonoids, which frequently occur in nature along with vitamin C. Quercetin in conjunction with vitamin C reportedly helps to reduce the severity of symptoms in individuals with hay fever.
Some individuals with allergic conditions have been found to have lower delta-6 desaturase enzyme activity, which inhibits the conversion of alpha linolenic acid (omega-3) and linoleic acid (omega-6) to their longer-chain metabolites. This in turn inhibits the production of the important anti-inflammatory prostaglandins. Clinical trials indicate that appropriate fatty acid supplementation often alleviates a broad range of allergic-type inflammatory conditions.
Alpha linolenic Acid :Also known as omega-3, it is the precursor to the series 3 prostaglandins (PGE3), which are anti-inflammatory in nature. The omega-3/omega-6 fatty acid ratios tend to be out of balance in the diets of many people in the United States. Proper adjustments of dietary fatty acids can play a key role in the successful management of inflammation associated with atopic diseases. This involves decreasing the intake of oils high in omega-6 (corn, safflower, and sunflower oils) and increasing the intake of omega-3. Flaxseed oil is a rich source of omega-3 as well as fish oils. A minimum of an extra 400 IU of natural vitamin E should be taken daily when consuming supplemental omega-3.
Gamma linolenic acid (GLA): This is the elongated metabolite of linoleic acid (omega-6). Studies reveal that many people with allergic conditions have adequate plasma levels of linoleic acid, but a deficiency of GLA. This indicates reduced activity of the delta-6 desaturase enzyme activity resulting in a subsequent decrease in the conversion of omega-6 to GLA. The administration of supplemental GLA has proven to be of therapeutic benefit for patients with conditions such as atopic eczema. Two of the best sources of GLA are borage oil (23%) and evening primrose oil (10%).
Bifidobacteria, Lactobacillus acidophilus
Probiotics containing lactobacillus acidophilus, lactobacillus casei and bifidobacteria are important supplements for individuals with food allergies or intolerances. In one study, every child that was suffering from symptoms related to food allergies was found to have deficiencies of lactobacillus and bifidobacteria, along with an overgrowth of Enterobacteriaceae. Another study found that lactobacillus supplementation given to subjects with allergic rhinitis improved their allergy symptoms.
Herb.
Proanthocyanidins (PCO's), the active constituents in grape seed, are flavonoid-rich compounds and free radical scavengers. It has been reported to enhance the absorption of and work synergistically with vitamin C. It has been used for supportive care in allergies and asthma. PCO's have been reported to inhibit the release of mediators of inflammation, such as histamine, leukotrienes, and prostaglandins, mechanisms that would be beneficial in multiple inflammatory processes such as allergies and asthma. In contrast, a study involving forty-nine seasonal allergic rhinitis sufferers compared the effects of 100mg grape seed extract twice a day against placebo. The evaluation of multiple endpoints demonstrated no significant differences between the treatment and placebo groups. Proanthocyanidins are reported to neutralize several classes of free radicals, including hydroxyl, lipid peroxides, and iron-induced lipid peroxidation. They may inhibit the enzyme xanthine oxidase.
The freeze-dried leaf of stinging nettle has been used in relation to allergies, with some success. A randomized, double-blind study of 92 individuals reported that a freeze-dried preparation of stinging nettle leaf was superior to placebo in relieving the symptoms of allergic rhinitis (itching, watery eyes, runny nose).
Coleus is a relatively new medicinal herb in the United States, although it has been extensively researched in India over the last twenty years. There have been studies published supporting its hypotensive (blood pressure lowering) and spasmolytic effects. Most studies have been conducted with the isolated extract, forskolin, but current research supports that the whole plant may be actually more effective.
Homeopathic
Allium cepa
Typical Dosage: 6X or 6C, 30X or 30C
Burning nasal discharge, worse indoors; Eyes sensitive to light; Sneezing; Sensation of hook sticking in throat, worse with warm food or drinks
Arsenicum album
Typical Dosage: 6X or 6C, 30X or 30C
Feel worn out; Sneezing; Eyes sensitive to light
Arundo mauritanica
Typical Dosage: 6X or 6C, 30X or 30C
Itching; Burning eyes and runny nose; Ears and roof of mouth itch
Drosera rotundifolia
Typical Dosage: 6X or 6C, 30X or 30C
Profuse, fluid discharge; Sneezing
Histaminum
Typical Dosage: 6X or 6C, 30X or 30C
May counteract histaminic release in body
Kali bichromicum
Typical Dosage: 6X or 6C, 30X or 30C
Nasal congestion with thick, yellow discharge, crusts in nose; Headaches centered in the eyes
Sabadilla
Typical Dosage: 6X or 6C, 30X or 30C
Violent sneezing; Watery eyes; Puffy red eyelids; Headache, better from warm drinks
Ambrosia
Typical Dosage: 6X or 6C, 30X or 30C
General improvement of ragweed response including sneezing, burning eyes, and runny nose
Aromatherapy for Allergies
Many essential oils possess the following properties: Expectorant, mucolytic, antispasmodic, anti-inflammatory, anti allergenic, immune stimulating, and antibacterial. These properties suggest the effective use of essential oil therapy in allergies. The following oils may be used in a diffuser with a carrier oil, and inhaled as needed:
- Lavender (Lavendula augustifolia) 5 drops
- Bergamot (Citrus bergamia) 2 drops
- Lemon (Citrus Limonum) 1 drop
- Juniper (Juniperus communis) 1 drop
- Peppermint (Mentha piperta) 1 drop
Inhaled oils stimulate cilia on olfactory epithelium and thereby pass the message of smell on to the brain. Essential oils have the ability to stimulate any of the brain centers, evoking response.
Caution: Essential Oil therapies should not be used during pregnancy or lactation and should always be used under the direction of an experienced aromatherapist.
Diet and Lifestyle
- Avoid allergens as much as possible. There are a variety of air filtration devices for the home. Ozone purifiers and HEPA filtration are state of the art for home use in reducing mold, pollen, dander, and dust mites indoors.
- Reduce exposure to environmental pollutants, cigarette smoke, and other pollutants.
- Use hypoallergenic products whenever possible.
- Drink quality water, either filtered, reverse osmosis, or bottled.
Reduce intake of foods that increase arachidonic acid cascade such as meat.
Alopecia
Also listed as: Hair loss
Alopecia is the loss of hair. Hair loss can be caused by different reasons, including damage to the hair shaft or follicles. Fungal infections can also cause hair loss. There are two main types of alopecia. Alopecia areata occurs when the body’s immune system attacks hair follicles and causes hair to fall out. Androgenetic alopecia, on the other hand, is an inherited form of hair loss. With alopecia areata, hair can fall out in patches all over the body. With androgenetic alopecia, hair on the head thins and falls out. In men, this is called male pattern hair loss; in women, it is called female diffuse hair loss. About 60% of people with androgenetic alopecia are men. Hair loss caused by androgenetic alopecia is permanent.
Symptoms of alopecia may include:
- Male pattern hair loss: Thinning or complete loss of hair at the hairline and top of the head.
- Female diffuse hair loss: A gradual thinning of hair, especially on the top of the head. The hairline usually stays the same.
- Alopecia areata: Broken hairs, or hairs easily removed; one or more round or oval bald patches.
Causes may include:
- Aging
- Genetics
- Illness
- Some medications (such as chemotherapy)
- Malnutrition
- Autoimmune disorder (alopecia areata)
Usually your doctor can diagnose androgenetic alopecia by examining you and taking a medical history. If your doctor suspects alopecia areata, the doctor may order a fluorescent antinuclear antibody (FNA) test, which detects the presence of antibodies. If antibodies are present, it is a sign of an autoimmune disorder.
Treatment depends on the type of alopecia you have. With many temporary forms of alopecia, hair will grow back without treatment. For people with alopecia areata, medications may help reduce hair loss. Some men with male pattern hair loss may consider surgery, such as hair transplants, scalp reduction, and strip or flap grafts.
Complementary and Alternative Therapies
These therapies have only limited success in treating male pattern baldness.
Nutrition and Supplements
For alopecia areata
- Biotin (300 mcg per day) and trace minerals, such as those found in blue-green algae (2 - 6 tablets per day), may promote hair growth. Biotin and zinc aspartate have been used to treat alopecia areata in children. However, there is no evidence that biotin will help if you are already getting enough biotin in your diet. Biotin is found in chard, romaine lettuce, carrots, and tomatoes.
For androgenetic alopecia
- Beta-sitosterol (50 mg two times per day) and saw palmetto (200 mg two times per day) appear to help hair growth in men with male pattern hair loss. In one study, men who took this combination had greater hair growth than men who took placebo. If you take other medications -- particularly hormone therapy -- talk to your doctor before taking this combination.
Herbs
The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, herbs should be taken with care, under the supervision of a healthcare practitioner.
For androgenetic alopecia
- Saw palmetto (Serenoa repens), 200 mg and beta-sitosterol, 50 mg, two times per day (see Nutrition and Supplements).
For alopecia areata
- Aromatherapy -- One study found that massaging the scalp with a combination of several essential oils improved hair growth. The oils used were lavender, rosemary, thyme, and cedarwood. Because essential oils can be toxic, they are mixed with a “carrier” oil -- in this case, jojoba or grapeseed oil -- before applying to skin. Add 3 - 6 drops of essential oil to 1 tbs. of jojoba or grapeseed oil. Massage into scalp daily.
Massage
Therapeutic massage increases circulation (helping bring more blood to the scalp) and reduces stress. Scalp massage using essential oils of rosemary, lavender, thyme, and cedarwood may help increase circulation (see Herbs).
Some men using finasteride (Propecia) may have a decreased sex drive or trouble getting an erection.
If you are pregnant, postpone treatment until after your baby is born.
Alzheimer's disease
Signs and Symptoms
Alzheimer's disease is a progressive, degenerative brain disease that results in loss of memory and mental function. It progresses in stages and people with Alzheimer's experience gradual memory loss as well as loss of judgment, difficulty concentrating, loss of language skills, personality changes, and a decline in the ability to learn new tasks. In advanced stages, people with Alzheimer's can lose all memory and mental abilities.
Alzheimer's in the most common kind of dementia. About 5 million Americans have Alzheimer's and this number is expected to increase as the population grows older. How it progresses is different for each person. If Alzheimer's develops rapidly, it is likely to continue to progress rapidly. If it has been slow to progress, it will likely continue on a slow course.
The effects of Alzheimer's come because the disease kills brain cells. In a healthy brain, billions of neurons generate chemical and electrical signals that are relayed from neuron to neuron and help a person think, remember, and feel. Neurotransmitters -- brain chemicals -- help these signals move from cell to cell. In people with Alzheimer's, neurons in certain places start to die, causing lower levels of neurotransmitters to be produced. That causes the brain to have problems with its signals.
There is no cure for Alzheimer's, but there are some medications that can help slow the progression of the disease in some people. Some herbs and supplements, and lifestyle adjustments, may help reduce the risk or improve quality of life.
Signs and Symptoms
The early symptoms of Alzheimer's disease can be missed because they resemble signs that many people attribute to "natural aging." The following are the most common signs and symptoms of Alzheimer's:
Psychological Symptoms
- Increasing memory loss, starting with forgetting recent events and new information, and progressing to not recognizing friends and family members
- Difficulty concentrating
- Difficulty understanding words, completing sentences, or finding the right words
- Getting lost in familiar surroundings
- Restlessness
- Depression
- Aggression, agitation, anxiety, restlessness
- Distrusting others
- Withdrawal, disinterest, hostility, loss of inhibitions
Physical Symptoms
- Impaired movement or coordination
- Muscle stiffness, shuffling or dragging feet while walking
- Insomnia or change in sleep patterns
- Weight loss
- Incontinence
- Muscle twitching or seizures
Researchers aren't sure what causes Alzheimer's disease. Both genetics and the environment may combine in some cases. Recent research indicates that free radicals (molecules that can cause oxidation, and damage cells and DNA) may play a role in the development of Alzheimer's.
Alzheimer's is characterized by the buildup in the brain of two types of proteins. Clumps of abnormal cells are called plaques, made of beta-amyloid protein. These plaques build up between neurons and may prevent them from communicating with each other. Inside nerve cells are tangles, made of twisted tau protein. Tau protein is necessary for the brain to function, but in people with Alzheimer's the protein becomes twisted, which may cause damage to neurons (brain cells).
People with the APOE-e4 gene are more likely to develop Alzheimer's -- it's known as a "risk gene" for the condition. But scientists think there may be many more genes involved. And even people without inherited genes for the disease can get Alzheimer's.
The causes and risk factors associated with Alzheimer's disease are not entirely clear, but include:
- Family history of Alzheimer's
- Older age -- the risk of developing Alzheimer's doubles every five years after age 65
- Long-term high blood pressure
- Heart disease
- History of head trauma -- one or more serious blows to the head may put a person at an increased risk.
- Down syndrome
- Education level -- people with higher levels of education are less likely to develop Alzheimer's
There is no single test for Alzheimer's disease. A true diagnosis can be made only after a person dies and an autopsy is performed on the brain.
However, Alzheimer's usually has a characteristic pattern of symptoms. A doctor will start by ruling out other possible causes. The doctor will ask questions about medical history and symptoms and do a physical exam (including a neurological exam).
The following tests may also be used:
- Mental status evaluation, to test memory and attention span. It can also reveal difficulties in problem-solving, social, and language skills.
- Genetic test, using a blood test for the APOE-e4 gene. The presence of the gene in the blood may suggest Alzheimer's, but it does not always make an accurate diagnosis.
- Imaging tests such as CT, MRI, or PET scans.
In the early stages of dementia, brain scans may be normal. In later stages, an MRI may show a decrease in the size of certain brain areas. While the scans do not confirm the diagnosis of Alzheimer's, they rule other causes of dementia such as stroke and tumor.
No one knows exactly how to prevent Alzheimer's disease, but eating a healthy diet and exercising regularly help.
- Eating more fatty, cold-water fish (such as tuna, salmon, and mackerel) may be associated with a lower risk of dementia. This may be because these fish have high levels of omega-3 fatty acids, which benefit the heart and the brain. Eating fish at least two to three times per week provides a healthy amount of omega-3 fatty acids.
- Antioxidants, such as vitamins A, E, and C (found in darkly colored fruits and vegetables), may help prevent damage caused by free radicals.
- Maintaining normal blood pressure levels may reduce the risk for Alzheimer's.
- Some studies suggest that certain medications may prevent Alzheimer's, including statin drugs (such as pravastatin or lovastatin, used to lower cholesterol) and nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. More research is needed to see how effective these medications are in reducing risk of the disease.
- Keeping mentally and socially active may help delay the onset or slow the progression of Alzheimer's.
The goals in treating Alzheimer's disease are to:
- Slow progression of the disease.
- Manage behavior problems, confusion, and agitation.
- Change the home environment to be safe.
- Support family members and other caregivers.
There is no cure for Alzheimer's. The most promising treatments include lifestyle changes and medications.
Lifestyle
Research indicates that the following lifestyle changes may help improve behavior in people with Alzheimer's disease:
- A regular walk with a caregiver or trusted companion may improve communication skills and lessen the chance of wandering.
- Bright light therapy may reduce insomnia and wandering.
- Calming music may reduce wandering and restlessness, boost brain chemicals, and improve behavior.
- Pets can increase appropriate social behaviors.
- Relaxation training and other exercises that require focused attention can improve social interaction and the ability to perform tasks.
The Safe Return Program, implemented by the Alzheimer's Association, encourages identification bracelets, wallet cards, and clothing labels for patients with Alzheimer's. Information is stored in a national database and distributed to authorities when a person is reported missing.
Nutrition and Dietary Supplements
People with Alzheimer's may need help with nutrition. They often forget to eat and drink, and, as a result, can become dehydrated.
Follow these tips for a healthy diet:
- Eat antioxidant foods, including fruits (such as blueberries, cherries, and tomatoes) and vegetables (such as squash and bell peppers).
- Eat foods high in B-vitamins and calcium, such as almonds, beans, whole grains (if no allergy), dark leafy greens (such as spinach and kale), and sea vegetables such as kelp and dulce.
- Eat more high-fiber foods, including beans, oats, root vegetables (such as potatoes and yams), and psyllium seed.
- Avoid refined foods such as white breads, pastas, and especially sugar.
- Eat fewer red meats and more lean meats, cold-water fish, tofu (soy, if no allergy), or beans for protein.
- Use healthy oils in foods, such as olive oil or vegetable oil.
- Reduce or eliminate trans-fatty acids, found in commercially baked goods such as cookies, crackers, cakes, French fries, onion rings, donuts, processed foods, and margarine.
- Avoid caffeine, alcohol, and tobacco.
- Drink 6 - 8 glasses of filtered water daily.
- Exercise at least 30 minutes daily, five days a week.
These supplements may help with some symptoms of Alzheimer's, although further study is needed:
- Phosphatidylserine, 100 mg three times per day, a substance occurring naturally in the brain, shows promise in several studies. This supplement may increase levels of brain chemicals that deal with memory, according to several studies. Do not take phosphatidylserine if you are taking anticoagulants (blood-thinners), and use caution if combining it with ginkgo for the same reason. There are great differences in quality among phosphatidylserine supplements. You should consider spending more for a more expensive brand, as they tend to be better than cheaper brands.
- Antioxidants may protect against the development of dementia. They may even slow the progression of dementia. In some, but not all, studies, vitamin E (400 - 800 IU per day) combined with Aricept may slow cognitive decline in people with Alzheimer’s disease. Another antioxidant, coenzyme Q10 (10 - 50 mg three times per day), may also help the brain get more oxygen. The skins of dark berries also provide valuable antioxidants. Many naturally-oriented physicians recommend eating half a cup of frozen blueberries daily -- freezing makes the antioxidants in the berries' skin more easily absorbed.
- Vitamins: biotin (300 mcg); B1 (50 - 100 mg), B2 (50 mg), B6 (50 - 100 mg), B12 (100 - 1,000 mcg), folic acid (400 - 1,000 mcg). No scientific evidence shows a direct benefit, but B12 and folic acid lower the levels of an amino acid in the blood that is often elevated in Alzheimer's patients. Injections of B12 may have the best results.
- Zinc (30 - 50 mg per day) is often deficient in elderly people, and may help improve memory.
Herbs
Herbs are generally a safe way to strengthen and tone the body's systems. As with any therapy, you should work with your health care provider to get your problem diagnosed before starting any treatment. You may use herbs as dried extracts (capsules, powders, teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, you should make teas with 1 tsp. herb per cup of hot water. Steep covered 5 - 10 minutes for leaf or flowers, and 10 - 20 minutes for roots. Drink 2 - 4 cups per day.
- Ginkgo (Ginkgo biloba), standardized extract, 40 - 50 mg three times per day, shows the best evidence for treating early Alzheimer's disease and vascular dementia. If you are taking blood-thinning medication, use ginkgo only under the supervision of your doctor.
- Huperzine A, a chemical made from the plant Huperzia serrata, may improve memory in both vascular and Alzheimer's dementia, according to several studies in China. However, more studies are needed to know for sure. The usual dose is 200 mcg twice a day. Do not take huperzine A if you have liver disease or if you are about to have anesthesia.
- American Ginseng (Panax quinquefolium) increases endurance and improves blood flow to the brain. Use with caution if you have high blood pressure, and talk to your doctor before combining ginseng with gingko.
- One study showed that lemon balm (Melissa officinalis), 60 drops per day, helped improve cognitive function in people with mild-to-moderate Alzheimer's.
- Bacopa (Bacopa monnieri) leaf extract, called Brahmi, is used in Ayurvedic or Indian medicine to improve brain function and learning. However, no scientific studies have looked at bacopa to see whether it might help lessen symptoms of dementia. One study found that 300 mg per day for 12 weeks seemed to improve cognition in healthy people.
- Vinpocetine (isolated from Vinca minor), 10 - 40 mg twice daily, may increase blood flow to the brain and help the brain better use oxygen. However, most of the studies done so far have been of poor quality. More research is needed.
Acupuncture
Small studies have shown that transcutaneous electrical nerve stimulation (TENS), a technique used in physical therapy and certain types of acupuncture, may improve memory and daily living skills in people with Alzheimer's. Further studies are needed.
Massage and Physical Therapy
People with Alzheimer's disease become frustrated and anxious because they cannot communicate well with language. Using touch, or massage, as a form of nonverbal communication has been shown to benefit those with Alzheimer's. In one study, people with Alzheimer's who received hand massages and were spoken to in a calming manner had a reduction in pulse rate and in inappropriate behavior. Health care professionals speculate that massage may be good for people with Alzheimer's not only because it is relaxing, but because it provides a form of social interaction.
Mind-Body Medicine
Music Therapy
Music therapy, the use of music to calm and heal, cannot slow or reverse dementia. But it may improve quality of life for both a person with Alzheimer's disease and their caregiver. Clinical reports suggest that music therapy may reduce wandering and restlessness and increase chemicals in the brain that enhance sleep and ease anxiety. For example, the chemicals melatonin, norepinephrine, and epinephrine increased in the brains of people with Alzheimer's after they listened to live music regularly. Mood also improved after listening to the music.
Support for the Caregiver
Studies suggest that caregivers who receive emotional support have better quality of life, and those they are caring for benefit as well.
Alzheimer's disease can lead to many complications, including:
- Falls
- "Sundowning" (withdrawal or agitation in the evening)
- Malnutrition and dehydration
- Infection (from urinary tract infections or pneumonia)
- Asphyxiation (stopped breathing)
- Harmful or violent behavior toward self or others
- Suicide
- Poor health and support due to caregiver burnout
- Physical and emotional abuse, including neglect
- Heart disease
Alzheimer's disease gets worse over time. However, people with the disease may survive for many years. Those with a long-standing history of high blood pressure are more likely to get worse faster.
Amenorrhea
Amenorrhea is the absence of menstruation (not having a period). There are two types of amenorrhea: primary and secondary. When a girl reaches age 16 and has not had a period, she may have primary amenorrhea. When a woman who has been having periods misses three in a row, she is considered to have secondary amenorrhea. Secondary amenorrhea is more common than primary amenorrhea. Amenorrhea is a sign of another condition, not a disease itself. Many things can cause it, from low body weight to hormonal imbalances to problems with the pituitary gland. Usually the underlying condition is not serious.
Signs and Symptoms
Symptoms of primary amenorrhea may include:
- Headaches
- Abnormal blood pressure
- Vision problems
- Acne
- Excessive hair growth
Symptoms of secondary amenorrhea may include:
- Nausea
- Swollen breasts
- Headaches
- Vision problems
- Being very thirsty
- Goiter (an enlarged thyroid gland)
- Darkening skin
Hot flashes, mood changes, depression, and vaginal dryness are common with estrogen deficiency.
What Causes It?
Both primary and secondary amenorrhea can have several causes.
Primary amenorrhea
- Lack of reproductive organs (such as uterus, cervix, or vagina)
- Problems with the pituitary gland
- Anorexia
- Stress
- Too much exercise
- Abnormal chromosones
Secondary amenorrhea
- Pregnancy or breast-feeding
- Using some kinds of birth control
- Taking some types of medication (such as corticosteroids)
- Hormone imbalance
- Low body weight
- Too much exercise
- Thyroid problems
- Pituitary tumor
- Stress
- Premature menopause (menopause before age 40)
What to Expect at Your Provider's Office
Your doctor may ask you to take a pregnancy test, then do a physical exam, which will include an internal pelvic exam. Your doctor may also order lab tests to check your hormone levels and see how your thyroid is functioning. Other tests may include computerized tomography (CT) scan, magnetic resonance imaging (MRI), or ultrasound.
Treatment Options
Your doctor will determine which treatment is right for you based on the underlying cause. Treatments include hormone therapy, psychological counseling and support, and surgery, among others.
Complementary and Alternative Therapies
Maintaining a proper weight and exercising the right amount can keep your body healthy. Other alternative therapies may help your body produce and use hormones properly.
Nutrition and Supplements
Be sure to eat a healthy diet: Eat fewer processed foods, and eat foods that are higher in unsaturated fat (but low in saturated fat). Avoid caffeine and alcohol. Eat more whole grains, vegetables, and omega-3 fatty acids (cold-water fish, nuts, and seeds). Diets that are very low in fat can raise your risk of amenorrhea. In addition, these supplements may help:
- Calcium (1,000 mg per day), magnesium (600 mg per day), vitamin D (200 - 400 IU per day), vitamin K (1 mg per day), and boron (1 to 3 mg per day). Women who don’t have periods are at higher risk of osteoporosis, and these vitamins and minerals may help keep bones strong.
- B6 (200 mg per day) may reduce high prolactin levels. Prolactin is a hormone released by the pituitary gland, and women with amenorrhea often have higher levels of prolactin.
- Essential fatty acids: Evening primrose or borage oil (1,000 - 1,500 mg one to two times per day).
Progesterone is sometimes available as an over-the-counter oral supplement. However, this is a hormone that should never be taken without your doctor's supervision.
Herbs
The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, take herbs only under the supervision of a health care provider.
Most of the herbs listed below have not been studied specifically for amenorrhea, but have been used traditionally. Many have an effect in the body that’s similar to the hormone estrogen. Talk to your doctor before taking them, and avoid these herbs if you have a history or family history of cancers associated with estrogen. That includes breast, cervical, uterine and ovarian cancer.
- For high prolactin levels: Chaste tree (Vitex agnus-castus) may help the pituitary gland function normally and may reduce prolactin levels, but it must be taken for 12 - 18 months. One very small study found that 10 of 15 women with amenorrhea started having periods after taking chaste tree for 6 months. If you already use hormone therapy, do not use chaste tree except under your doctor's supervision.
- These herbs have estrogen-like effects and are sometimes used to treat menopausal symptoms, although there are no clinical trials that show whether they work or are safe: Black cohosh (Cimicifuga racemosa), licorice, (Glycyrrhiza glabra), and squaw vine (Mitchella repens). Do not take licorice if you have high blood pressure or heart failure.
- Other herbs that may help stimulate menstrual flow include lady's mantle (Alchemilla vulgaris) and vervain (Verbena officinalis). Do not take these herbs without your doctor’s supervision. Your doctor should monitor your liver function if you take lady's mantle.
- Kelp (Laminaria hyperborea), oatstraw (Avena sativa), and horsetail (Equisetum arvense) are rich in minerals that may help promote thyroid function.
Wild yam is sometimes said to be a natural source of progesterone, but that is not true. Although it was once used to produce the hormone in the laboratory, the body cannot make progesterone from wild yam.
Avoid blue cohosh (Caulophyllum thalictroides). This toxic herb should not be used without strict medical supervision.
Homeopathy
There have been few studies examining the effectiveness of specific homeopathic remedies. Professional homeopaths, however, may recommend treatments for amenorrhea based on their knowledge and clinical experience. Before prescribing a remedy, homeopaths take into account a person’s constitutional type -- your physical, emotional, and intellectual makeup.
Pulsatilla -- for most menstrual problems, especially in women who have poor appetite and do not favor exertion; they may faint easily. They may be aggravated by heat and feel worse in the evening. They may like to be in the open air.
Sepia -- for women with late or irregular menstruation. They may have a sallow complexion and experience frequent headaches, toothaches, and pain when bearing down. They may feel cold and want to be alone.
Graphites -- for women with late or light menstruation. They may have a sallow complexion and experience a feeling of fullness or constipation and headaches. They often have a fair complexion.
Physical Medicine
The following help increase circulation and relieve pain from pelvic congestion:
- Castor oil pack. Apply oil to a soft, clean cloth, place on abdomen, and cover with plastic wrap. Place a hot water bottle or heating pad over the pack and let sit on your abdomen for 30 - 60 minutes. You can safely use this treatment for 3 days, although it may be beneficial to use for longer; talk to your health care provider to determine how long to use it.
- Contrast sitz baths. Use two basins that you can comfortably sit in. Sit in hot water for 3 minutes, then in cold water for 1 minute. Repeat this three times to complete one "set." Do one to two sets per day, 3 - 4 days per week.
Acupuncture
Acupuncture is believed to improve hormonal imbalances that can go along with amenorrhea, and related conditions, such as polycystic ovary syndrome (PCOS). A few small studies of women with fertility problems (which are sometimes connected with amenorrhea) suggest that acupuncture may help promote ovulation. Acupuncturists treat people with amenorrhea based on an individualized assessment of the excesses and deficiencies of qi located in various meridians. Acupuncturists believe that amenorrhea is often associated with liver and kidney deficiencies, and treatment often focuses on strengthening function in these areas.
Special Considerations
Becoming pregnant may be difficult or impossible. Amenorrhea also may cause pregnancy complications.
Amenorrhea can also raise the risk of developing osteoporosis.
Anaphylaxis
Anaphylaxis is a sudden, serious allergic reaction that can be life threatening. Symptoms may be mild to start, but they become severe in minutes, or even seconds. Occasionally, the symptoms develop gradually over 24 hours. The more quickly the symptoms begin, the more severe they generally are. Many people who are susceptible to anaphylaxis carry emergency medicine with them. Anaphylaxis is a medical emergency, and although rare, it causes about 500 deaths each year.
Signs and Symptoms
- Itching (often the first symptom), redness, hives, swelling, sweating
- Swelling in the nose or throat, hoarseness, wheezing, difficulty speaking, trouble breathing, chest tightness
- Abnormal heart rate or rhythm, shock, heart attack
- Stomach cramps, nausea, vomiting, diarrhea
- Dizziness, fainting
What Causes It?
Anaphylaxis occurs when your immune system overreacts to an allergen. Your body releases substances to protect you from the allergen, but instead cause your blood pressure to drop suddenly and your airways to constrict so that you have trouble breathing.
Many substances can causes anaphylaxis; sometimes the cause isn't known. Common triggers include:
- Antibiotics (especially penicillin)
- Aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen), and prescription opiate pain medications (such as codeine)
- Foods, such as nuts, shellfish, milk, eggs, and berries
- Insect bites or stings
- Egg-based vaccines
- Latex (as in condoms, rubber gloves)
- Food coloring and preservatives (such as tartrazine, also known as FDC yellow dye No. 5)
Anaphylaxis is rare. The following factors may increase your risk for anaphylaxis:
- Known allergies
- Cardiovascular disease
- Women
- Substance abuse
- Asthma
- Initial exposure to the allergen by injection (intravenous medication)
- Frequent exposure to the allergen, particularly if frequent exposure is followed by a long delay and then a re-exposure
What to Expect at Your Provider's Office
Your health care provider will perform an exam, ask about any contact you may have had with possible allergens (food, drugs, insect stings), and may conduct blood or urine tests, allergy tests, or other tests.
Treatment Options
Prevention
- Avoid any substances that have triggered a previous allergic response.
- If you have allergies or suspect you do, see a specialist to be tested.
- Take medicines by mouth instead of by injection whenever possible.
- If you have a history of anaphylaxis, your doctor should coach you and your family members on how to use self-injectable epinephrine. You should carry a syringe loaded with adrenaline (epinephrine) to inject immediately after exposure to a known allergen, or at the first sign of a reaction. Also, wear a Medic Alert bracelet to alert others that you have a history of this condition. One study suggested that patients at risk of food-induced anaphylaxis carry 2 doses of epinephrine.
Treatment Plan
Get emergency medical care right away to maintain breathing, blood pressure, and heart function, and to reverse the reaction.
Drug Therapies
You should receive epinephrine right away. Once at the hospital, your health care provider may give you additional drugs, including antihistamines and corticosteroids, to control symptoms and prevent delayed relapse.
Surgical and Other Procedures
For breathing trouble, health care providers may need to open the airway with an endotracheal tube and possibly connect a ventilator. Other procedures may be needed to stabilize blood pressure.
Complementary and Alternative Therapies
Anaphylaxis always requires conventional emergency medical care and should not be treated with CAM therapies. However, some CAM therapies may help prevent allergic responses, including anaphylaxis, or lessen the severity of an allergic reaction. Keep in mind, though, that some herbs and supplements -- just like prescription drugs -- can cause allergic reactions, including anaphylaxis. If you have allergies, talk to your health care provider before taking any herbs or supplements.
Nutrition and Supplements
The following nutrients may help support your immune system and reduce or prevent allergic reactions, though there is no scientific evidence that they will help prevent anaphylaxis:
- Quercetin (400 - 500 mg per day in divided doses) -- a flavonoid and antioxidant found in many plants that may help reduce allergic reactions. Some people may get more benefit from the water-soluble form of quercetin, called quercetin chalcone.
- Vitamin C (1,000 mg 2 - 6 times per day for a short period) -- Supports immune system function and also enhances the effect of quercetin. Lower the dose if diarrhea develops.
- Zinc (30 mg per day) -- Animal studies suggest that zinc may help protect against gastrointestinal symptoms (stomach cramps, nausea, vomiting, or diarrhea) that sometimes accompany anaphylaxis.
Herbs
Some herbs may help support your immune system and reduce the frequency or severity of allergic reactions, although there is no evidence they can prevent anaphylaxis. Anaphylaxis is a medical emergency and should never be treated with herbs.
- Alpinia galanga (2 - 4 g per day) -- One of several plants commonly called galangal used as a spice in Thai food, Alpinia galanga is a member of the ginger family. Preliminary animal studies suggest it may have some antihistamine properties. Take capsules or drink tea. To make tea, steep 1 g in 1 cup boiling water for 10 minutes, strain, and cool.
- Ashwagandha (Withania somnifera, 1 - 6 g per day) -- An antioxidant that supports immune system function and may have antihistamine properties. Ashwagandha can interact with other herbs and prescription medications, so take it only under your doctor's supervision. Do not take ashwagandha if you are pregnant or trying to become pregnant, or if you take thyroid medication or corticosteroids (prednisone).
- Chinese skullcap (Scutellaria baicalensis, 1 - 2 g per day) -- May have antihistamine properties
- Licorice (Glycyrrhiza glabra, 100 - 300 mg per day) -- Has been used traditionally to support the immune system and may have antihistamine properties. Do not take licorice if you have high blood pressure or heart disease.
- Stinging nettle (Urtica dioica, 300 mg 4 times per day) -- Has anti-inflammatory and antihistamine properties. Look for freeze-dried encapsulated nettles, which are believed to retain most of the antihistamine effects of the plant.
Several studies suggest that medicinal plants traditionally used in Asia to prevent or treat allergic reactions may help prevent anaphylaxis. These herbal remedies include:
- Sweet chestnut tree (Castanea crenata) -- contains quercetin, and reduced skin and blood vessels reactions related to anaphylaxis in animal studies.
- Spreading sneezeweed (Centipeda minima) -- contains flavonoids, and is used in Traditional Chinese Medicine for its anti-inflammatory and antihistamine effects.
- Asian rose (Rosa davurica) -- traditionally used to support the immune system. It inhibited anaphylaxis in an animal study.
- Hardy orange (Poncirus trifoliata) -- used traditionally for treatment of allergies. Animal studies have shown inhibition of anaphylaxis.
Researchers have tested combinations of specific herbs in animals, which show some signs of preventing anaphylaxis. You should consult a licensed, qualified herbalist for more information about these combinations.
Herbs to avoid
You can also have an allergic reaction to the following herbs:
- Arnica flower (Arnica montana)
- Artichoke leaf (Cynara scolymus) -- in those with an allergy to artichokes
- Blessed thistle herb (Cnicus benedictus)
- Cayenne pepper (Capsicum spp.)
- Cinnamon bark (Cinnamomum verum)
- Dandelion root or herb (Taraxacum officinale) -- may trigger a reaction in those with latex allergy
- Echinacea (Echinacea purpurea)
- Fennel oil and fennel seed (Foeniculum vulgare)
- Feverfew (Tanacetum parthenium/Chrysanthemum parthenium)
- Ginkgo biloba leaf extract
- Poplar bud (Populus spp.) -- may trigger a reaction in those with salicylate (aspirin) sensitivity
- Psyllium seed (Plantago spp.) -- allergic response more common with powder or liquid form
- St. John's wort (Hypericum perforatum)
- Yarrow (Achillea millefolium)
Homeopathy
Anaphylaxis requires immediate emergency medical attention. While the following homeopathic remedies have been used for allergic reactions, including symptoms of anaphylaxis, they should be given only under the guidance of a certified, trained homeopath in the appropriate circumstances. Before prescribing a remedy, homeopaths take into account a person's constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
- Aconitum -- helps alleviate the tremendous anxiety and fear of dying that may occur during or immediately following an anaphylactic reaction
- Arnica montana -- may be used in the case of shock or following a traumatic experience
- Apis mellifica -- for puffy, rapidly swelling skin following an insect bite or sting.
Acupuncture
Acupuncture has been used to support the immune system and to relieve symptoms of seasonal allergies, as well as to lessen chronic allergies and sensitivities. One animal study found that electroacupuncture (applying an electrical charge to acupuncture needles) seemed to help animals survive allergic shock, compared to no treatment at all. While you should never delay conventional treatment of anaphylaxis, this study suggests acupuncture may be a useful supportive therapy. More research is needed.
Without proper treatment, anaphylaxis can be deadly. However, most people who receive proper treatment do well. Once you have anaphylaxis, you may not have it again, even with exposure to the same allergen. But the risk is high, so try to avoid any substances that caused the reaction. Drugs classified as beta-blockers, monoamine oxidase inhibitors, ACE inhibitors, and ARBs may make anaphylaxis worse or interfere with treatment. If you have a history of anaphylaxis, check with your doctor or pharmacist to find out if you take one of these medications.
You may need to stay in the hospital for 24 hours to make sure no new symptoms will occur. For a severe reaction, your doctor may monitor heart function or admit you to the intensive care unit.
Anemia
Anemia occurs when your blood does not have enough red blood cells to properly carry oxygen to your organs and tissues. Because your body doesn’t get enough oxygen, you feel tired -- one of the primary symptoms of anemia.
Your blood contains three types of cells -- white blood cells, which fight off infection; platelets, which help blood to clot; and red blood cells, which carry oxygen from your lungs throughout your body. Red blood cells are made in your bone marrow. They contain hemoglobin, an iron-based protein that helps blood cells carry oxygen. With anemia, your body either doesn’t make enough red blood cells or loses them faster than they can be replaced.
There are several types of anemia. The most common type is iron deficiency anemia, caused by a lack of iron in your body. Other types include:
- Vitamin deficiency anemia, megaloblastic anemia -- caused by a lack of folic acid and vitamin B12 in your body.
- Anemia of chronic disease -- caused when certain chronic diseases (such as cancer, kidney failure, or Crohn’s disease) interfere with the production of red blood cells.
- Aplastic anemia -- caused when bone marrow loses its ability to produce all three types of blood cells. Aplastic anemia is life threatening.
- Hemolytic anemias -- caused when red blood cells are destroyed faster than the bone marrow can replace them.
- Sickle cell anemia -- caused by a defective type of hemoglobin that makes red blood cells form a crescent or sickle shape. These sickle cells die early, meaning the body is always short of red blood cells. The abnormal shape can block blood flow through small vessels, causing pain. Sickle cell anemia is an inherited condition that affects mainly people of African, Mediterranean, Arabic, or South American descent.
Signs and Symptoms
Symptoms of anemia can be mild at first, and can be mistaken for other symptoms of other conditions. They include:
- Tiredness
- Weakness
- Shortness of breath
- Pale skin
- Lightheadedness
- Headache
- Feeling cold
- Rapid heartbeat and chest pain
What Causes It?
Anemia may have the following causes:
- Iron deficiency anemia -- Blood loss, such as from an ulcer or heavy menstruation or after surgery; not getting enough iron in your diet; pregnancy; side effect of medication
- Vitamin deficiency anemia -- Not getting enough folic acid and vitamin B12 in your diet, or being unable to absorb these vitamins (due to celiac disease, for example); side effect of medication
- Aplastic anemia -- may be caused by an autoimmune disorder
- Hemolytic anemia -- can be caused by medication, autoimmune disorders
- Sickle cell anemia – inherited
What to Expect at Your Provider's Office
Anemia is often caused by an underlying disease. Your doctor will draw blood and run lab tests, including a complete blood count (CBC) that measures the amount of red blood cells and hemoglobin in your blood. If you are anemic, your doctor may run more tests to determine what type of anemia you have.
Treatment Options
Treatment depends on the cause of the anemia and how serious it is. Your doctor may suggest changes in your diet to make sure you receive all of the nutrients you need for healthy blood formation, such as vitamin B12, iron, and folic acid. Your doctor may also suggest nutritional supplements or medication. If your anemia is due to an underlying disease, your doctor will treat that disease.
Complementary and Alternative Therapies
Most cases of anemia are either iron deficient or vitamin deficient. Making changes in your diet or taking supplements usually help. You should, however, already have the underlying cause of anemia diagnosed so you can start the right treatment. For example, too much iron is toxic, and you should not take supplements unless you have iron deficiency anemia and your doctor recommends them. Herbal and nutritional treatments may help when used along with medical treatment.
Nutrition and Supplements
Iron -- ferrous fumarate, glycerate, or sulfate are the forms of iron your body can absorb most easily. Always ask your doctor before taking an iron supplement. Taking a smaller dose three times a day may reduce side effects, as can taking iron with meals. If you miss a dose, don't take an extra dose the next time. Never take a double dose of iron. Keep iron supplements away from children. Even a little excess iron can be fatal. Dietary sources of iron include red meat (especially calf liver), beans, beet greens, blackstrap molasses, almonds, and brewer's yeast. Green leafy vegetables contain both iron and folic acid.
Vitamin C (250 - 500 mg 2 times per day) helps your body absorb iron. Dietary sources include citrus fruits and juices, tomatoes, broccoli, and cauliflower.
Vitamin B12 (1,000 mcg via injection once a day for 1 - 2 weeks, then every 1 - 3 months; or orally, 1,000 - 2,000 mcg per day) helps in cases of vitamin deficient or pernicious anemia. Dietary sources include liver, meats, eggs, tuna, and cheese. People with pernicious anemia cannot absorb the proper amount of vitamin B12 and may need lifelong supplements.
Folic acid (400 - 1,000 mcg per day) -- for folic acid deficiency, which can cause anemia. Good food sources include green leafy vegetables, orange juice, and grains. Taking folic acid supplements can mask vitamin B12 deficiency, so always take vitamin B12 when taking folic acid.
Blackstrap molasses, also known as pregnancy tea (1 tbs. per day in a cup of hot water), is a good source of iron, B vitamins, and minerals. Blackstrap molasses is also a very gentle laxative.
Herbs
The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, take herbs only under the supervision of a health care provider.
Spirulina, or blue-green algae, may treat some anemias. Dose is 1 heaping tsp. per day.
Alfalfa (Medicago sativa), dandelion (Taraxacum officinale) root or leaf, burdock (Arctium lappa), and yellowdock (Rumex crispus) have traditionally been used to fortify and cleanse the blood. For mild cases of anemia, they may help bring levels of hemoglobin into normal range. Dosage is 1 tbs. per cup of water. Simmer roots for 20 minutes and leaves for 5 minutes. You may use a single herb, or a combination of these four herbs.
Gentian (Gentiana lutea) is often used in Europe to treat anemia by stimulating the digestive system to more easily absorb iron and other nutrients. Chinese herbalists do not use gentian if someone has chronic pain or frequent urination. Add 1 tsp. powdered dried rhizome to 3 cups of water. Take 1 tbs. about a half hour before eating.
Homeopathy
Although few studies have examined the effectiveness of specific homeopathic therapies, professional homeopaths may consider the following remedies for the treatment of anemia based on their knowledge and experience. Before prescribing a remedy, homeopaths take into account a person's constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
A homeopath will usually consider anemia as symptomatic of an underlying condition, and treat that condition.
- Ferrum phosphoricum -- for iron deficiency
- Calcarea phosphorica -- particularly for children with nighttime bone aches, cool hands and feet, lack of energy, or poor digestion
Following Up
Eating a normal, balanced diet is very important if a nutrition problem is causing your anemia. You should avoid drugs that can cause stomach problems and too much alcohol if they are causing your anemia.
Special Considerations
Complications from anemia can range from loss of productivity due to weakness and fatigue to coma and death.
Pregnant women need more iron and folic acid than normal. A folic acid deficiency during pregnancy can result in infants being born with neural-tube defects, such as spina bifida.
Angina
Angina is chest pain caused by restricted blood flow to the heart (called ischemia). It usually occurs when you are under emotional or physical stress (such as exercise). The heart doesn't get enough oxygen from the coronary arteries, and you feel a squeezing chest pain or pressure across your chest, which usually goes away after you stop the activity. The most common cause of angina is atherosclerosis (hardening of the arteries).
Stable angina usually occurs when you exercise and is fairly predictable. It is relieved with rest or nitroglycerin. Unstable angina, on the other hand, can occur when you are resting, or at unpredictable times. It can lead to a heart attack, so if you experience unstable angina you should immediately call 911.
It can be difficult to determine whether your chest pain is something serious or whether it is a milder condition. For that reason, you should always see your doctor for a diagnosis and treatment. Angina can lead to a heart attack, so you should never try to diagnose or treat it on your own.
Signs and Symptoms
Chest pain from angina can feel like pain due to other causes such as heartburn, a muscle strain, or asthma. When in doubt, assume that the pain is related to your heart until proven otherwise, especially if you are experiencing pain that you have never felt before.
The classic chest pain from angina feels like significant pressure, squeezing, or tightness in the center of your chest. It has been described as feeling like a band across the chest or a weight pressing down on the chest. You may also feel pain in your left arm and shoulder, neck, and jaw. Other possible feelings include indigestion, rapid or skipping heartbeat, or mild discomfort.
Causes
Coronary heart disease, which occurs when the arteries leading to the heart become narrowed or blocked by plaque, is almost always the cause of angina.
Risk Factors
The risk factors for angina are the same as the risk factors for developing heart disease, including:
- Age
- Male gender
- Menopause
- Family history of heart disease
- Diabetes
- Smoking or exposure to second hand smoke
- High cholesterol
- High blood pressure
- Obesity
- Sedentary lifestyle
- Stress
- Thyroid disease
See articles on Atherosclerosis and Heart Attack for more information about risk factors.
Diagnosis
Your doctor may run several tests to determine the cause of your chest pain.
Electrocardiogram (ECG), which records heart activity through electrodes fastened to your chest.
Stress test, which measures how your heart performs when you exert yourself. You will be hooked up to an ECG machine and may be asked to exercise (usually on a treadmill or stationary bike), or you may be given a drug that causes your heart to act as it does when you exercise. The stress test also may be done with imaging (like thallium, sestimibi, or an echocardiogram) to look at the blood flow and muscle function of your heart.
Coronary catheterization, which examines arteries to see if they are narrowed or blocked, involves injecting a dye into your arteries through a thin catheter.
Other tests may include an electron beam computed tomography (EBCT) scan or cardiovascular magnetic resonance imaging (MRI).
Preventive Care
If you will be doing an activity that usually triggers your angina, your doctor may tell you to take nitroglycerin a few minutes in advance to prevent the pain.
The best prevention for angina is to modify as many risk factors for heart disease as possible:
- Stop smoking
- Maintain a proper weight
- Control blood pressure, diabetes, and cholesterol
- Eat a diet low in saturated fats, and high in whole grains, fiber, fruits, and vegetables
- Exercise at least 30 minutes per day, 5 days per week
- Reduce stress
In treating angina, your doctor will treat the underlying heart disease to prevent it from getting worse. By doing this, blood flow to the heart improves and angina gets better. Lifestyle changes and certain medications can improve blood flow and make you feel better fairly quickly. Keep track of what causes your angina pain, what it feels like, how often you get it, and how long it lasts. If there's a change in your pattern for the worse (for example, if it happens more frequently or with less exertion), let your doctor know right away.
Lifestyle
Changing your diet, exercising regularly, and practicing relaxation techniques to reduce your response to stress can help improve blood flow to your heart and reduce angina. These steps can also help treat your risk factors for heart disease.
Diet
A diet low in saturated fat and high in whole grains, fruits, and vegetables will help your heart and also keep your weight under control. The American Heart Association recommends that you do the following to prevent or treat heart disease:
- Eat a variety of nutritious foods from all the food groups, especially whole grains, fruits and vegetables, and low fat dairy products.
- Eat at least 2 servings of fish per week
- Limit sodium intake to 2,300 mg per day.
- Limit alcohol intake to 2 drinks per day for men and 1 drink per day for women.
- Burn as many calories as you take in. Get at least 30 minutes of exercise most days (or, better still, every day).
Relaxation
Relaxation techniques may help you reduce stress, which can be a contributing factor to heart disease, and relieve chest pain. Such practices might include the use of meditation, progressive muscle relaxation, breathing exercises, yoga, self hypnosis, or biofeedback.
Nutrition and Dietary Supplements
Eat a well balanced diet with plenty of whole grains, fruits, vegetables, and low fat dairy products. If approved by your physician, make sure you exercise at least 30 minutes a day most days of the week.
There are many supplements that can help reduce your chances of developing heart disease and its consequences, including angina.
A few supplements are being studied specifically to reduce the pain from angina. However, you should never try to treat angina on your own, and should only take supplements or herbs under your doctor's supervision. The doses given below are ones that have been used in studies; it is important to talk to your doctor about what dose might be best for you.
- L-carnitine (1 g 2 times per day), an amino acid, may help reduce symptoms of angina, according to several clinical trials.
- Coenzyme Q10 or CoQ10 (150 mg per day) is important for heart health and several studies suggest that taking it may allow people with angina to exercise more without pain. High doses of CoQ10 may interfere with some anticoagulants (blood thinners), so talk to your doctor before taking CoQ10 if you take anticoagulants.
- Arginine or l-arginine (2 g 3 times per day) is another amino acid that may improve blood flow and increase exercise tolerance in people with angina.
- Magnesium (365 mg 2 times per day) acts similar to a calcium-channel blocker in the body, although it is much weaker. One study suggested it may help reduce chest pain caused by exercise. Magnesium can lower blood pressure and cause diarrhea, so talk to your doctor before taking it.
Herbs
The use of herbs is a time honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, you should take herbs with care, under the supervision of a health care practitioner. If you have angina, do not take any herbs without your doctor's supervision.
There are several different herbs that may be helpful for the treatment and prevention of heart disease, including those that help you reduce your cholesterol, blood pressure, and other risk factors. See articles on Atherosclerosis, Heart attack, High blood pressure, and High cholesterol for more information. Herbs that may be helpful for angina include:
- Hawthorn (Crataegus monogyna, 60 mg 3 times per day) has been used traditionally as a to treat heart disease. One small clinical trial suggested that people with angina who took hawthorn improved blood flow to the heart and were better able to exercise without pain. However, the trial was small and more studies are needed. Hawthorn can cause side effects and interact with other drugs, so do not take it without your doctor's supervision.
- Kudzu (Pueria lobota, 30 mg - 120 mg per day) has been used in Chinese medicine for centuries to treat heart disease. A few clinical trials have indicated that kudzu may reduce the frequency of angina in people, but the trials were poorly designed. More research is needed. Kudzu can cause side effects and interact with other drugs, so do not take it without your doctor's supervision.
- Terminalia arjuna, an herb used in Ayurvedic medicine, was shown in one study to be as effective as isosorbide mononitrate (Imdur) in reducing the number of angina attacks and increasing exercise capacity. However, more studies are needed.
- Suxiao jiuxin wan is widely used in China for angina. One study found that suxiao jiuxin wan improved ECG measurements and reduced symptoms and frequency of acute angina attacks compared with nitroglycerin.
Homeopathy
Homeopathy should never be used instead of immediate medical attention for unstable angina, new onset chest pain, or chest pain that has changed in intensity, frequency, or other characteristics. Homeopathy may, however, be used to help reduce your risk of heart disease, along with other medications. Although few studies have examined the effectiveness of specific homeopathic remedies, professional homeopaths would recommend appropriate therapy to lower high blood pressure and cholesterol. Before prescribing a remedy, homeopaths take into account your constitutional type. In homeopathic terms, a person's constitution is his or her physical, emotional, and intellectual makeup. An experienced homeopath would assess all of these factors when determining the most appropriate remedy for you as an individual.
Acupuncture
Studies using acupuncture to treat angina have found mixed results. While some show no benefit, others have found that acupuncture may help reduce the frequency of angina attacks and the need to use nitroglycerin.
Prognosis and Complications
Stable angina can progress and become unstable and even lead to a heart attack. The good news, however, is that with the right treatment including eating proper diet, getting enough exercise, and taking medication, blood flow to the heart can dramatically improve, lessening the likelihood of angina attacks.
Anorexia nervosa
People with anorexia have an extreme fear of gaining weight, which causes them to try to maintain a weight far less than normal. They will do almost anything to avoid gaining weight, including staving themselves or exercising too much. People with anorexia have a distorted body image -- they think they are fat (even when they are extremely thin) and won't maintain a proper weight.
Anorexia is an emotional disorder that focuses on food, but it is actually an attempt to deal with perfectionism and a desire to control things by strictly regulating food and weight. People with anorexia often feel that their self-esteem is tied to how thin they are.
Anorexia is increasingly common, especially among young women in industrialized countries where cultural expectations encourage women to be thin. Fueled by popular fixations with thin and lean bodies, anorexia is also affecting a growing number of men, particularly athletes and those in the military.
Anorexia most commonly affects teens, as many as 3 in 100. Although anorexia seldom appears before puberty, associated mental conditions, such as depression and obsessive-compulsive behavior, are usually more severe when it does. Anorexia is often preceded by a traumatic event and is usually accompanied by other emotional problems. Anorexia is a life-threatening condition that can result in death from starvation, heart failure, electrolyte imbalance, or suicide.
It can be a chronic disease, one that you deal with over your lifetime. But treatment can help you develop a healthier lifestyle and avoid anorexia's complications.
Signs and Symptoms
The primary sign of anorexia nervosa is severe weight loss. People with anorexia may try to lose weight by severely limiting how much food they eat. They may also exercise excessively. Some people may engage in binging and purging, similar to bulimia. They may vomit after eating or take laxatives. At the same time, the person may insist that they are overweight.
Physical Signs
- Excessive weight loss
- Scanty or absent menstrual periods
- Thinning hair
- Dry skin
- Cold or swollen hands and feet
- Bloated or upset stomach
- Downy hair covering the body
- Low blood pressure
- Fatigue
- Abnormal heart rhythms
- Osteoporosis
Psychological and Behavioral Signs
- Distorted perception of self (insisting they are overweight when they are thin)
- Being preoccupied with food
- Refusing to eat
- Inability to remember things
- Refusing to acknowledge the seriousness of the illness
- Obsessive-compulsive behavior
- Depression
What To Watch For
- Skipping meals or making excises not to eat
- Eating only a few foods
- Refusing to eat in public
- Planning and preparing elaborate meals for others but not eating
- Constantly weighing themselves
- Ritually cutting food into tiny pieces
- Compulsive exercising
Causes
No one knows exactly what causes anorexia. Medical experts agree that several factors work together in a complex fashion to lead to the eating disorder. These may include:
- Severe trauma or emotional stress (such as the death of a loved one or sexual abuse) during puberty or prepuberty.
- Abnormalities in brain chemistry. Serotonin, a brain chemical that's involved in depression, may play a role
- A cultural environment that puts a high value on thin or lean bodies.
- A tendency toward perfectionism, fear of being ridiculed or humiliated, a desire to always be perceived as being "good." A belief that being perfect is necessary in order to be loved.
- Family history of anorexia. About one-fifth of those with anorexia have a relative with an eating disorder.
Risk Factors
- Age and gender -- anorexia is most common in teens and young adult women.
- Dieting
- Weight gain
- Unintentional weight loss
- Puberty
- Living in an industrialized country
- Having depression, obsessive-compulsive disorder (OCD) or other anxiety disorders -- OCD is present in up to two-thirds of people with anorexia. OCD associated with an eating disorder is often accompanied by a compulsive ritual around food (such as cutting it into tiny pieces).
- Participation in sports and professions that prize a lean body (such as dance, gymnastics, running, figure skating, horse racing, modeling, wrestling, acting)
- Difficulty dealing with stress (pessimism, tendency to worry, refusal to confront difficult or negative issues)
- History of sexual abuse or other traumatic event
- Experiencing a big life change, such as moving or going to a new school
Diagnosis
People with anorexia may think they are in control of their disease and don't want any help. But if you or a loved one is experiencing signs of anorexia, it's important to seek help. If you are a parent who suspect your child has anorexia, take your child to see the doctor immediately. If your doctor suspects anorexia, your doctor will order several laboratory tests as well as do a psychological evaluation. The SCOFF questionnaire, developed in Great Britain, is sometimes used when anorexia is suspected. A "yes" response to at least two of the following questions is a strong indicator of an eating disorder:
- S: "Do you feel sick because you feel full?"
- C: "Do you lose control over how much you eat?"
- O:"Have you lost more than 13 pounds recently?"
- F: "Do you believe that you are fat when others say that you are thin?"
- F: "Does food and thoughts of food dominate your life?"
Lab tests may include:
Blood tests -- to look for signs of anemia, to check electrolytes, and to check liver and kidney function
Electrocardiogram -- to look for abnormal heart rhythms
Bone density test -- to check for osteoporosis
If your doctor makes a diagnosis of anorexia, your doctor will likely ask you to work with a multidisciplinary team including a doctor, a psychologist or psychiatrist, and a registered dietitian.
Preventive Care
The most effective way to prevent anorexia is to develop healthy eating habits and a strong body image from an early age. Don't accept cultural values that place a premium on thin, perfect bodies. Make sure you and your children are educated about the life-threatening nature of anorexia.
For people who have already developed anorexia, the primary goal is to avoid relapse.
- Family and friends should be urged not to focus on the person's condition or on food or weight. Don't discuss anorexia at mealtimes, for example. Instead, devote mealtimes to social interaction and relaxation.
- Watch for signs of relapse. Careful and frequent monitoring of weight and other physical signs by your doctor can catch problems early.
- Cognitive behavioral therapy or other forms of psychotherapy can help the person develop coping skills and change unhealthy thought processes.
- Family therapy can help with any problems in the home that may contribute to the person's anorexia.
Treatment
The most successful treatment is a combination of psychotherapy, family therapy, and medication. It is important for the person with anorexia to be actively involved in their treatment. Many times the person with anorexia doesn't think they need any treatment. Even if they do, anorexia is a long-term challenge that may last a lifetime. People remain vulnerable to relapse when going through stressful periods of their lives.
A combination of treatments can give the person the medical, psychological, and practical support they need. Cognitive-behavioral therapy, along with antidepressants, can be an effective treatment for eating disorders. Complementary and alternative therapies may help with nutritional deficiencies.
If the person's life is in danger, hospitalization may be needed, particularly under the following circumstances:
- Continuing weight loss, in spite of outpatient treatment
- Body mass index (BMI) -- 30% below normal. The normal range is a BMI of 19 - 24. BMI is a measurement that takes into account a person's height and weight.
- Irregular heart rhythm
- Severe depression
- Suicidal tendencies
- Low potassium levels
- Low blood pressure
Even after some weight gain, many people with anorexia remain quite thin and risk of relapse is very high. Several social influences may make recovery difficult:
- Friends or family who admire how thin the person is
- Dance instructors or athletic coaches who put a premium on having a very lean body
- Denial on the part of parents or other family members
- The person's belief that extreme thinness is not only normal but also attractive, and that purging is the only way to avoid becoming overweight
Involving friends, family members, and others in the treatment can help deal with these issues.
Lifestyle
Treating anorexia nervosa involves major lifestyle changes:
- Establishing regular eating habits and a healthy diet
- Sticking with your treatment and meal plans
- Developing a support system and participating in a support group for help with stress and emotional issues
- Ignoring the urge to weigh yourself or check your appearance constantly
- Cutting back on exercise if obsessive exercise has been part of the disease. Once the person has gained weight, the doctor may set a controlled exercise program to help overall health.
Nutrition and Dietary Supplements
People with bulimia are more likely to have vitamin and mineral deficiencies, which can affect their health. Vitamin deficiencies can contribute to cognitive difficulties such as poor judgment or memory loss. Getting enough vitamins and minerals in your diet or through supplements can correct the problems.
Always tell your doctor about the herbs and supplements you are using or considering using, as some supplements may interfere with conventional treatments.
Following these nutritional tips may help overall health:
- Avoid caffeine, alcohol, and tobacco.
- Drink 6 - 8 glasses of filtered water daily.
- Use quality protein sources -- such as meat and eggs, whey, and vegetable protein shakes -- as part of a balanced program aimed at gaining muscle mass and preventing wasting.
- Avoid refined sugars, such as candy and soft drinks.
Your doctor may suggest addressing nutritional deficiencies with the following supplements:
- A daily multivitamin, containing the antioxidant vitamins A, C, E, the B-vitamins and trace minerals, such as magnesium, calcium, zinc, phosphorus, copper, and selenium.
- Omega-3 fatty acids, such as fish oil, 1 - 2 capsules or 1 tablespoonful oil two to three times daily, to help decrease inflammation and improve immunity. Cold-water fish, such as salmon or halibut, are good sources; eat two servings of fish per week.
- Coenzyme Q10, 100 - 200 mg at bedtime, for antioxidant, immune, and muscular support.
- 5-hydroxytryptophan (5-HTP), 50 mg two to three times daily, for mood stabilization. Talk with your health care provider if you are on prescription medications before taking 5-HTP. Do not take 5-HTP if you are taking antidepressants.
- Creatine, 5 - 7 grams daily, when needed for muscle weakness and wasting.
- Probiotic supplement (containing Lactobacillus acidophilus among other strains), 5 - 10 billion CFUs (colony forming units) a day, for maintenance of gastrointestinal and immune health. Refrigerate probiotic supplements for best results.
- L-glutamine, 500 - 1000 mg three times daily, for support of gastrointestinal health and immunity.
Herbs
Herbs are generally a safe way to strengthen and tone the body's systems. As with any therapy, you should work with your health care provider to get your problem diagnosed before starting any treatment. You may use herbs as dried extracts (capsules, powders, teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, you should make teas with 1 tsp. herb per cup of hot water. Steep covered 5 - 10 minutes for leaf or flowers, and 10 - 20 minutes for roots. Drink 2 - 4 cups per day. You may use tinctures alone or in combination as noted.
- Ashwagandha (Withania somniferum) standardized extract, 450 mg one to two times daily, for general health benefits and stress.
- Fenugreek (Trigonella foenum-graecum), 250 - 500 mg two to three times daily, to stimulate appetite.
- Cayenne pepper (Capsicum annuum) standardized extract, 400 mg three times daily, for help with digestion.
- Milk thistle (Silybum marianum) seed standardized extract, 80 - 160 mg two to three times daily, for liver health.
- Catnip (Nepeta spp.), as a tea two to three times per day, to calm the nerves and soothe the digestive system.
Homeopathy
No scientific literature supports the use of homeopathy for bulimia. However, an experienced homeopath will consider your individual case and may recommend treatments to address both your underlying condition and any current symptoms.
Mind-Body Medicine
Cognitive Behavioral Therapy
Cognitive behavioral therapy is one of the most effective therapies for anorexia. In cognitive behavioral therapy, the person learns to replace negative, unrealistic thoughts and beliefs with positive, realistic ones. The person is also encouraged to acknowledge their fears and to develop new, healthier ways of solving problems.
Family Therapy
In addition to individual therapy for someone who has anorexia, family therapy that involves parents and siblings is also recommended. Parents and other family members often have intense feelings of guilt and anxiety that they need to address. Family therapy is aimed, in part, at helping the parents or partner (in the case of an adult) understand the seriousness of this illness and the ways in which family patterns may contribute to it.
Hypnosis
Hypnosis may be helpful as part of an integrated treatment program for anorexia nervosa. Hypnosis may help the person strengthen both self-confidence and the ability to cope. That may result in healthier eating, improved body image, and greater self-esteem.
Biofeedback
Studies suggest that biofeedback may be helpful in reducing stress in people with anorexia.
Anxiety
Anxiety is a general feeling of being worried. Everyone experiences anxiety once in a while. People with generalized anxiety disorder (GAD), however, feel anxious frequently or excessively, not necessarily because of a particular situation. For them, anxiety interferes with their daily activities.
Signs and Symptoms
Symptoms of anxiety may include:
- Muscle tension, trembling
- Feeling restless or on edge
- Fast heartbeat (tachycardia)
- Fast or troubled breathing (dyspnea)
- Stomach upset
- Having a hard time concentrating
- Headache
- Sweating
- Fatigue
- Irritability
- Trouble falling asleep or staying asleep
What Causes It?
Many things can cause anxiety -- for example, some medications may cause you to be anxious, or an underlying medical condition may prompt feelings of anxiety. Scientists aren't sure what causes GAD, although they think that certain chemicals in the brain (called neurotransmitters), including serotonin and norepinephrine, may be involved. Genes, your environment, and your life situation may also contribute to GAD.
What to Expect at Your Provider's Office
Your doctor or mental health provider will talk to you about when you feel anxious and what it feels like. Your health care provider will take your medical history, give you a physical examination, and may take blood or urine samples for laboratory tests. Sometimes, you will have an electrocardiogram (EKG) to rule out heart problems. You may be asked to fill out a psychological questionnaire.
For someone to be diagnosed with GAD, the person must meet the following criteria:
- Excessive anxiety or worry most days for at least 6 months
- Difficulty controlling anxiety
- Anxiety associated with three or more of the following symptoms: feeling restless, being fatigues, having trouble concentrating, being irritable, having muscle tension, or having trouble sleeping
- Anxiety that interferes with your daily life
- Anxiety that is not related to another psychological condition, such as panic attacks
- Anxiety that is not related to another physical condition, such as substance abuse
Treatment Options
Treatment for anxiety depends on the cause. If you have an underlying physical condition, your doctor will treat it. If your anxiety has no physical cause, your doctor may recommend counseling to help you learn coping strategies and problem-solving techniques. A 2007 review of studies that used cognitive behavioral therapy to treat anxiety found that it was effective for GAD. In cognitive behavioral therapy, you learn to modify or replace anxious thoughts with healthy ones. Your doctor may also suggest trying relaxation techniques, such as deep breathing. Sometimes, your doctor may prescribe medications to help until you have learned these techniques.
Complementary and Alternative Therapies
Mind-body techniques, nutrition, exercise, and herbs may help reduce anxiety. Progressive muscle relaxation, diaphragmatic breathing, biofeedback, meditation, and self-hypnosis can help you relax and reduce your anxiety.
Exercise
Several studies suggest that exercise is effective in reducing depression, and at least one 2007 study found that regular, intense exercise (running or playing football, for example) can also have a positive effect on anxiety. The benefits lasted up to 5 years.
Nutrition
Although there is no diet to relieve anxiety, eating healthy meals keeps your body well nourished and strong. Avoid caffeine because it can make you feel restless. Avoid alcohol and nicotine as well. Eat more fresh vegetables, whole grains, and fruits. Keep your blood sugar at a steady level by eating frequent small meals that contain protein, complex carbohydrates, and healthy fats.
Herbs
The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and interact with other herbs, supplements, or medications. For these reasons, take herbs only under the supervision of a health care provider.
- Valerian (Valeriana officinalis, 150 mg 2 - 3 times per day) is an herbal treatment for insomnia that is sometimes used to treat anxiety as well, although evidence is mixed. Some studies show that valerian does help reduce anxiety, but one study found that valerian was no better at reducing social anxiety than placebo. Valerian is often combined with lemon balm (Melissa officinalis) or with St. John's wort (Hypericum perforatum) for treating mild-to-moderate anxiety. Valerian may interact with other drugs that have a sedative effect, such as benzodiazepines, barbiturates, narcotics, antidepressants, and antihistamines. Do not take valerian if you are pregnant or nursing. Valerian can also affect the liver, so do not take it if you have liver problems. St. John's wort can affect other drugs you may be taking, including antidepressants, birth control, or other medications. You should avoid St. John's wort while pregnant or nursing. Talk to your doctor before using St. John's wort with any other medications.
- Passionflower (Passiflora incarnata) -- In a few studies, passionflower was as effective as some of the benzodiazepines in relieving anxiety. However, more studies are needed to know for sure whether passionflower is effective.
- Kava kava (Piper methysticum, 100 - 200 mg 2 - 4 times a day) is sometimes suggested for mild-to-moderate anxiety, but the Food and Drug Administration (FDA) has issued a warning concerning kava's effect on the liver. In rare cases, severe liver damage has been reported. Talk to your doctor before taking kava, and don’t take it for more than a few days.
- Other herbs sometimes suggested for anxiety include ginger (Zingiber officinalis), chamomile (Matricaria chamomilla), and licorice (Glycyrrhiza glabra). Avoid licorice if you have heart failure, heart disease, kidney or liver disease, or high blood pressure. Do not take licorice if you take a diuretic (water pills), anticoagulant (blood thinner), or antidepressant such as Prozac.
Essential oils of lemon balm, bergamot, and jasmine are calming, and you can use them as aromatherapy. Place several drops in a warm bath or atomizer, or on a cotton ball.
Homeopathy
Although few studies have examined the effectiveness of specific homeopathic therapies, professional homeopaths may consider the following remedies for the treatment of anxiety based on their knowledge and experience. Before prescribing a remedy, homeopaths take into account a person's constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
- Aconitum -- for anxiety accompanied by irregular or forceful heartbeat, shortness of breath, or fear of death.
- Arsenicum album-- for excessive anxiety that has no clear cause and is accompanied by restlessness, especially after midnight. It also may be used for perfectionists, including children, who worry about everything.
- Phosphorus-- for an impending sense of doom and anxiety when alone. It also may be used for impressionable adults and children who are easily influenced by the anxiety of others.
- Lycopodium-- for performance and other types of anxiety in those who are insecure, yet hide their low self-esteem with arrogance and bravado. It also may treat children with anxiety accompanied by bedwetting.
- Gelsemium-- for performance anxiety resulting in diarrhea, headache, dizziness, weakness, shakiness and trembling, or trouble speaking.
- Argentum nitricum-- for performance anxiety (such as before tests in school-age children) with rapid heart rate, feeling of faintness, diarrhea, or flatulence.
Acupuncture
Some evidence shows that acupuncture may help reduce symptoms of anxiety, especially when combined with behavioral therapies (including psychotherapy). One study showed that benefits lasted as long as one year after treatment. Acupuncturists treat people with anxiety based on an individualized assessment of the excesses and deficiencies of qi located in various meridians. With anxiety, a qi deficiency is often detected in the kidney or spleen meridians. In addition to performing needling techniques, acupuncturists may also use lifestyle and breathing techniques as well as herbal and dietary therapy.
Massage
Therapeutic massage can help reduce anxiety and stress.
Following Up
Follow your health care provider's instructions, and practice relaxation techniques as needed.
Special Considerations
Be sure to tell your health care provider if you are pregnant. Call your provider if you experience any significant side effects from prescribed medications.
Avoid kava kava, valerian, and St. John's wort if you are pregnant or nursing.
Atherosclerosis
Atherosclerosis is a slow disease in which your arteries become clogged and hardened. Fat, cholesterol, calcium, and other substances form plaque, which builds up in arteries. Hard plaque narrows the passage that blood flows through. That causes arteries to become hard and inflexible (atherosclerosis is also known as hardening of the arteries). It leads to cardiovascular disease, which is the leading cause of death in people over 45. Soft plaque is more likely to break free from the artery wall and cause a blood clot, which can block blood flow to vital organs.
The effects of atherosclerosis differ depending upon which arteries in the body narrow and become clogged with plaque. If the arteries that bring oxygen-rich blood to your heart are affected, you may have coronary artery disease, chest pain, or a heart attack. If the arteries to your brain are affected, you may have a transient ischemic attack (TIA) or a stroke. If the arteries in your arms or legs are affected, you may develop peripheral artery disease. You may also develop a bulge in the artery wall (aneurysm).
Lowering blood pressure and LDL ("bad") cholesterol levels, eating a healthy diet with lots of fruits and vegetables, quitting smoking, losing weight, and getting more exercise can prevent atherosclerosis.
Signs and Symptoms
Many times, people with atherosclerosis have any symptoms until an artery is 40% clogged with plaque. Symptoms vary depending upon which arteries are affected.
Coronary Artery Disease
Symptoms of coronary artery disease (where the heart arteries are narrowed) are usually brought on by physical exercise, sexual activity, exposure to cold weather, anger, or stress. The most common symptoms include:
- Chest pain (generally a heavy, squeezing, or crushing sensation with possible burning or stabbing pains)
- Abdominal, neck, back, jaw, or shoulder/arm pain
- Weakness
- Perspiration
- Shortness of breath
Cerebrovascular Disease
Cerebrovascular disease (where the arteries that supply the brain with blood) are narrowed) can cause transient ischemic attack (a sudden loss of brain function with complete recovery within 24 hours) and stroke. Symptoms may include:
- Weakness or paralysis on one side of the body
- Trouble speaking or understanding speech
- Loss of vision in one eye
- Muscle weakness
- Sudden trouble walking
- Dizziness
- Loss of balance or coordination
- Sudden severe headache
Peripheral Artery Disease
Peripheral artery disease affects the arteries that supply the arms and legs with oxygen-rich blood. Symptoms may include:
- Pain, aching, cramps, numbness or sense of fatigue in the leg muscles (intermittent claudication)
- "Bruits" (blowing sounds your doctor can hear with a stethoscope that indicate turbulence in blood flow)
- Hair loss
- Thickened nails
- Smooth, shiny skin surface
- Skin that is cold to the touch
- Gangrene
What Causes It?
No one knows the exact cause of atherosclerosis, although they do know what causes it to get worse. Many researchers believe it begins with an injury to the innermost layer of the artery, known as the endothelium. These factors are thought to contribute to the damage:
- High blood pressure
- Elevated LDL ("bad") cholesterol
- An accumulation of homocysteine (an amino acid produced by the human body, thought to be a risk factor for heart disease, stroke, osteoporosis, diabetes, and dementia)
- Smoking
- Diabetes
- Inflammation
Once the artery is damaged, blood cells called platelets build up there to try and heal the injury. Over time, fats, cholesterol, and other substances also build up at the site, which thickens and hardens the artery wall. The blood flow through the artery is decreased, and the oxygen supply to organs also decreases. Blood clots may form, blocking the artery or entering your bloodstream and cut off blood supply to other organs.
Because some people do not have the classic risk factors of atherosclerosis (such as cigarette smoking and high blood pressure), it is possible that there may be other causes, such as an infection. Research is ongoing.
Risk Factors
Risk factors for atherosclerosis include:
- Being male
- If female, being past menopause
- High blood pressure
- High LDL ("bad) cholesterol or triglycerides (fats in the blood)
- Diabetes
- Being overweight
- Smoking
- A family history of heart disease
- Elevated homocysteine levels
- Sedentary lifestyle
- Diets high in saturated fat and trans fatty acids (trans fats)
- Depression
What to Expect at Your Provider's Office
Your doctor can determine your risk for heart disease by conducting some tests. Blood tests can show high levels of cholesterol, homocysteine, and blood clotting factors. A stress test (also known as an exercise tolerance test) monitors your heart rate and blood pressure while you walk on a treadmill or ride a stationary bicycle. An electrocardiogram (ECG) is used during a stress test to detect abnormal heart rhythms, scar tissue in the heart muscle from a prior heart attack, and areas of decreased blood flow to the heart. Imaging techniques used during a stress test (such as an ultrasound) can pinpoint areas where blood flow to the heart may be decreased. An angiogram (or angiography), where your doctor injects a dye into your arteries and then performs a chest x-ray, can reveal areas of damage and plaque buildup.
Preventive Care
You can prevent atherosclerosis by living a healthy lifestyle.
- Stop smoking.
- Exercise at least 30 minutes a day, 6 days a week.
- Eat healthy foods, such as fruits, vegetables and whole grains that are low in saturated fat and high in fiber.
- Maintain a normal weight (or lose weight if you need to).
- Reduce stress.
- If you have high blood pressure, high cholesterol, diabetes or another chronic condition, work with your doctor to keep it in check.
Treatment Options
Healthy lifestyle choices (see "Preventive Care" section) are important in preventing and treating atherosclerosis. Your doctor may prescribe drugs to lower your cholesterol or blood pressure and to prevent complications. Nutrition and dietary supplements can help when used along with certain medications. Some herbs have also shown promise in lowering cholesterol levels and reducing the risk of heart disease.
Complementary and Alternative Therapies
Nutrition and Supplements
Healthy eating habits can help reduce high cholesterol, high blood pressure, and overweight -- three of the major risk factors for heart disease. The American Heart Association (AHA) has developed dietary guidelines that help lower fat and cholesterol intake and reduce the risk of heart disease. The AHA does not recommend very low-fat diets because research shows that people benefit from unsaturated ("good") fats, such as those found in olive oil, in their diet.
Many fad diets are popular, but they may not help you lose weight and keep it off -- and in some cases, they may not even be healthy. Any healthy diet will include a variety of foods. If a diet bans an entire food group (such as carbohydrates), it's probably not healthy.
For healthy eating, eat a balanced diet that contains the following:
- Grains: 6 - 8 servings per day (half should be whole grains)
- Vegetables: 3 - 5 servings per day
- Fruits: 4 - 5 servings per day
- Fat-free or low-fat dairy: 2 - 3 servings per day
- Lean meat, poultry, seafood: 3 - 6 oz. per day (about the size of a deck of cards)
- Fats and oils: 2 - 3 tbsp. per day (use unsaturated fats such as olive oil or canola oil)
- Nuts, seeds, legumes: 3 - 5 servings per week
- Sweets, sugars: 5 or fewer servings per week (the fewer, the better)
In addition, the AHA also recommends eating 2 servings of fatty fish (such as salmon or lake trout) per week; holding sodium (salt, including salt already added to food) to less than 2,400 mg per day; and limiting alcohol intake to one drink a day for women and two for men.
Diets for People with High Blood Pressure
People with high blood pressure especially need to lower the amount of sodium in their diet. The DASH diet (Dietary Approaches to Stop Hypertension) emphasizes a diet rich in fruits, vegetables, and low-fat or non-fat dairy products that provide high intake of potassium, magnesium, and calcium sources. Sodium intake should be between 1,500 - 2,400 mg per day (the lower, the better). Weight loss, regular physical activity, and limiting alcohol are also very important factors for lowering blood pressure.
Mediterranean Diet
The Mediterranean style diet concentrates on whole grains, fresh fruits and vegetables, fish, olive oil, and moderate, daily wine consumption. The Mediterranean style diet is not low-fat. Instead, it is low in saturated fat but high in monounsaturated fat. It appears to be heart-healthy: In a long-term study of 423 patients who had a heart attack, those who followed a Mediterranean style diet had a 50 - 70% lower risk of recurrent heart disease compared with people who received no special dietary counseling.
The TLC (Therapeutic Lifestyle Changes) Diet
This diet is recommended for people who have high cholesterol. With the TLC diet, less than 7% of your daily total calories should come from saturated fat, and only 25% -35% of your daily calories should come from fat, overall. Sodium should be limited to 2,400 mg per day. If these steps don't lower your cholesterol, your doctor may suggest adding more soluble fiber to your diet, along with plant sterols (found in cholesterol-lowering margarines and salad dressings).
Supplements and Vitamins
Talk with your doctor before taking any of these vitamins, minerals, or supplements to make sure they are right for you; to establish the proper dose for your condition; and to make sure they do not interact with any prescription drugs, or herbs or supplements you also might be taking.
Folic acid (400 mcg per day), vitamin B6 (25 - 100 mg per day), vitamin B12 (2 - 100 mcg per day) -- The B vitamins help the body break down homocysteine, an amino acid that's been linked to increased risk of heart disease and stroke. Researchers think that homocysteine may also contribute to atherosclerosis by damaging artery walls, thus causing blood clots to form -- but so far they haven't found a definite link. Researchers also don't yet know whether taking B vitamins reduces the risk of atherosclerosis or heart disease, nor do they know how much might have an effect. If you have a number of risk factors for heart disease, talk to your doctor about checking your homocysteine levels and whether your doctor would recommend a B complex vitamin supplement. In the meantime, be sure to get enough B vitamins through your diet by eating fruits and leafy green vegetables every day.
Omega-3 fatty acids, found in fish oil (1 - 4 g per day) -- There is good evidence that omega-3 fatty acids (namely EPA and DHA) found in fish oil can help prevent and treat atherosclerosis by preventing the development of plaque and blood clots. Omega-3s can also help prevent heart disease, lower blood pressure, and reduce the level of triglycerides (fats) in the blood. One preliminary study found that people with high cholesterol who took fish oil and red yeast rice lowered cholesterol levels about as much as people who took simvastatin (Zocor). The AHA recommends that people eat at least two servings of fatty fish (such as salmon) per week. People with heart disease or those who need to lower triglycerides may need to take fish oil supplements. Because fish oil at high doses can increase the risk of bleeding, talk to your doctor before taking a high dose (more than 1 g per day), especially if you already take blood-thinning medication.
Beta-sitosterol (800 mg to 6g per day in divided doses about 30 minutes before meals) -- Beta-sitosterol is a plant sterol, a compound that can stop cholesterol from being absorbed by the intestines. A number of well-designed scientific studies have shown that beta-sitosterol does lower "bad" LDL cholesterol levels in the body. Beta-sitosterol may lower the amount of vitamin E and beta-carotene absorbed by the body, so you may want to ask your doctor if you need to take extra E or beta-carotene.
Potassium -- Your body needs potassium to keep electrolytes balanced and for nerves to function properly. Some diuretics may cause the body to get rid of too much potassium. If you take a prescription diuretic, your doctor may also recommend a potassium supplement. But be sure to check with your doctor before taking a potassium supplement if you take a diuretic. High levels of potassium can be dangerous.
Policosanol (5 - 10 mg two times per day) -- Policosanol is a mix of waxy alcohols usually derived from sugar cane and yams. Several studies have indicated it may lower "bad" LDL cholesterol and possibly even raise "good" HDL cholesterol. One study found that policosanol was equivalent to fluvastatin (Lescol) and simvastatin (Zocor) in lowering cholesterol levels. It may also stop blood clots from forming. However, most studies have been conducted in Cuba by a research group that uses a proprietary form of policosanol and is funded by the manufacturer, so it is hard to evaluate the evidence. Policosanol may increase the risk of bleeding, and should not be taken by people who also take blood-thinning medication.
Antioxidant vitamins (beta-carotene, C, E) -- Some large, observational studies have suggested that people who consume more antioxidant vitamins have a lower risk of heart disease than those who consumer lower amounts. However, no studies have shown a cause-and-effect relationship.
- Beta-carotene -- While some studies suggest that eating a diet high in beta-carotene (found in yellow, orange, and dark green vegetables) may protect against atherosclerosis, other studies show it may increase the risk for people who smoke or drink a lot of alcohol. Researchers think that eating vegetables with beta-carotene also provides the body with other antioxidants that may have the protective effect, while just taking a supplement does not.
- Vitamin C -- Several studies suggest that eating a diet high in vitamin C can help protect against heart disease. But there is no evidence that taking extra vitamin C through a supplement will help.
- Vitamin E -- One randomized, placebo-controlled study failed to show any reduction in heart disease among people who took vitamin E. However, researchers are still studying the effects of vitamin E on heart disease risk.
Selenium (100 - 200 mcg per day) -- Some studies show that people who consume more selenium in their diet have a lower risk of heart disease, but again, researchers haven't shown a cause-and-effect relationship. And one study found that taking selenium for a long time significantly increased the risk of developing type 2 diabetes. Talk to your doctor before taking extra selenium.
Coenzyme Q10 (CoQ10) -- Researchers believe that CoQ10 may inhibit blood clot formation and boost levels of antioxidants. One study found that people who received daily CoQ10 supplements within 3 days of a heart attack were much less likely to experience subsequent heart attacks and chest pain. They were also less likely to die of the condition than those who did not receive the supplements. Still, more research is needed to say whether CoQ10 has any role in preventing or treating atherosclerosis. People who take statins may have lower amounts of CoQ10 in their bodies and may consider taking a supplement. If you take statins, ask your doctor if you need a CoQ10 supplement.
Polyphenols -- Polyphenols are chemical substances found in plants that have antioxidant properties. Test tube, animal, and some population-based studies suggest that the flavonoids quercetin, resveratrol, and catechins (all found in high concentration in red wine) may help reduce the risk of atherosclerosis by protecting against the damage caused by LDL cholesterol. However, more studies in humans are needed to confirm these findings.
One study of resveratrol in mice found that it protected against age-related damage to vital organs, including the heart and liver, even when the mice ate a high-fat diet. Although this study is promising, researchers need to confirm its findings and to see whether resveratrol would have the same effect in humans. No one is sure how much resveratrol you would need to see if there is any benefit. In addition, resveratrol may have estrogen-like effects, and researchers don't yet know whether it would pose the same risks as estrogen supplements.
Vitamin D -- Some preliminary studies suggest that vitamin D may also help protect against heart disease, but researchers aren't sure why. One observational study found that women over the age of 65 who took vitamin D supplements to protect against osteoporosis had one-third less risk of dying from heart disease as women who did not take the supplements. And a recent study found that a vitamin D deficiency was associated with an increased risk of heart disease, especially among people with high blood pressure.
Herbs
- Hawthorn (Crataegus monogyna, 160 - 1,800 mg per day in two or three divided doses) -- Hawthorn contains the polyphenols rutin and quercetin, and was used traditionally to treat cardiovascular diseases. Animal and laboratory studies show that hawthorn has antioxidant properties that help protect against the formation of plaques and may help lower high cholesterol and high blood pressure. Talk to your doctor before taking hawthorn, as it can interact with other drugs taken for heart disease and high blood pressure.
- Garlic (Allium sativum, 900 mg per day of garlic powder, standardized to 0.6% allicin) -- Some clinical trials have shown that fresh garlic and garlic supplements may lower cholesterol levels, prevent blood clots, and destroy plaque. However, other studies show mixed evidence, and one 2007 study showed no effect at all. Garlic can increase the risk of bleeding and should not be taken if you are also taking blood-thinning medication.
- Olive leaf extract(Olea europaea, 1000 mg per day) -- One study found that people with mild high blood pressure (hypertension) lowered cholesterol and blood pressure by taking olive leaf extract, compared to those who took placebo. More research is needed to confirm this study's findings.
- Red yeast or red yeast rice (Monascus purpureus, 1,200 mg two times per day with meals) -- Several studies indicate that a proprietary form of red yeast (Cholestin) can lower cholesterol levels, and that the herb acts like the prescription drugs statins (See "Medications" section). For that reason, you should not take red yeast without a doctor's supervision, especially if you already take statins to lower cholesterol.
- Psyllium (Plantago psyllium, 10 - 30 g per day in divided doses taken 30 - 60 minutes after meals) -- Taking psyllium, a type of fiber, helps lower cholesterol levels as well as blood sugar levels. If you take medicine for diabetes, talk to your doctor before taking psyllium.
- Guggul (Commiphora mukul, 3 - 6 g per day) -- Guggul is used in Ayurvedic medicine to treat high cholesterol levels. Scientific studies have found mixed results -- guggul appears to work in Indian populations, but not in people who eat Western-style, high-fat diets.
Acupuncture
Acupuncture may help reduce risk factors for heart disease. It can help people who want to quit smoking. Some studies indicate that it may aid in weight loss as well as lowering cholesterol and blood pressure.
Homeopathy
Although few studies have examined the effectiveness of specific homeopathic remedies, professional homeopaths would recommend appropriate treatments to reduce the risk of atherosclerosis based on their knowledge and experience. Homeopathic prescriptions for atherosclerosis would include remedies to lower high blood pressure and cholesterol. Before prescribing a remedy, homeopaths take into account a person's constitutional type. In homeopathic terms, a person's constitution is his or her physical, emotional, and intellectual makeup. An experienced homeopath would assess all of these factors when determining the most appropriate remedy for each individual.
Other Considerations
Prognosis and Complications
Some complications of atherosclerosis include:
- Heart disease
- Heart failure
- Abnormal heart rhythms
- Stroke
- Heart attack
- Poor blood supply to certain parts of the body (such as the legs or intestines)
- Kidney failure
- Death
The outlook for atherosclerosis varies from person to person. People with atherosclerosis should work closely with their doctor to make the right lifestyle changes and, if needed, take the proper medications to control their condition and avoid complications.
Osteoarthritis (OA) is the most common kind of arthritis. It is a joint disease caused by “wear and tear.” Healthy cartilage -- the firm, rubbery tissue that cushions bones at joints -- allows bones to glide over one another, while cartilage absorbs energy from the physical movement. In OA, cartilage breaks down and wears away. As a result, the bones rub together causing pain, swelling, and stiffness.
OA may also limit the range of motion in affected joints. Most often, OA develops in the hands, knees, hips, and spine.
Both men and women get OA about equally. It is a common condition, especially as you get older. Symptoms tend to show up when people are in their 50s and 60s, although an injury to a joint or overuse (such as some athletes might experience) can cause OA when you are younger. More than 20 million people in the United States have OA.
Signs and Symptoms
Signs and symptoms of OA may include the following:
- Joint pain (often a deep, aching pain) that gets worse when you move and better when you rest the joint (in severe cases, a person may experience constant pain)
- Stiffness in the morning or after sitting or lying down for more than 15 minutes
- Joint swelling
- Joints that are warm to the touch
- Limited range of motion
- Muscle weakness (caused by favoring the painful joint)
- Growth of bony knobs near joints (such as Heberden's nodes, in which bumps appear on the outermost finger joints)
Causes
Most of the time, the cause of OA is unknown. It is associated with aging. However, metabolic, genetic, chemical, and mechanical factors can play a role in its development.
Risk Factors
Risk factors for OA include:
- Being older
- Genetic predisposition
- Being overweight
- Injury to the joint
- History of inflammatory joint disease
- Metabolic or hormonal disorders (such as hemochromatosis and acromegaly)
- Bone and joint disorders present at birth
- Repetitive stressful joint use (such as athletes or construction workers might experience)
- Deposits of uric acid crystals in joints
Diagnosis
There is no single test to diagnose OA, so most doctors use a combination of methods to diagnose the disease and rule out the possibility other causes. A physical exam can show limited range of motion, grating of a joint with motion, joint swelling, and tenderness. An x-ray of affected joints will show loss of the joint space and, in advanced cases, wearing down of the ends of the bone and bone spurs.
Preventive Care
You may reduce the risk of developing OA by:
- Protecting an injured joint from further damage
- Exercising
- Losing weight and maintaining a proper weight
- Avoiding repetitive motions
Treatment
While researchers are working on ways to regrow cartilage, those treatments aren’t yet available. Current goals when treating OA are to relieve pain and improve range of motion of the joint. Specific treatment depends upon which joint is affected. A combination of conventional treatment and complementary and alternative medicine (CAM) may be most effective.
These lifestyle changes may help you manage OA:
Losing weight -- Losing any extra weight helps relieve the pressure on your joints and may slow down the loss of cartilage as well as relieve pain. If you have OA and are overweight, losing weight is one of the best things you can do to help your condition.
Exercise -- Although it may seem hard to think about exercise when you are in pain, regular exercise is another good thing you can do when you have OA. Exercise strengthens the muscles so they better support your joints. Several clinical studies support the value of exercise for people with OA. Clinical studies also suggest that in addition to reduction of pain and disability, exercise improves strength, range of motion, balance and coordination, endurance, and posture. Walking is a great exercise, or, if walking is too painful, try warm-water exercise. Water supports your joints and the warmth is soothing. Also, gentle range of motion exercises can increase your flexibility and decrease pain in affected joints. Your doctor may recommend physical therapy for specific joints.
Nutrition and Dietary Supplements
Eating a balanced, healthy diet can help reduce inflammation in your body and may also help you lose weight or maintain a proper weight. These diet tips can help:
- Eat more foods that decrease inflammation, including garlic, onions, watercress, horseradish, mustard, parsley, celery, rose hips tea, pickles, lemon, and anti-inflammatory oils (nuts, seeds, cold-water fish).
- Avoid refined foods, such as white breads, pastas, and sugars.
- Eat fewer red meats and more lean meats, cold-water fish, tofu (soy, if no allergy) or beans for protein.
- Eat more fruits, vegetables, and whole grains.
- Use healthy cooking oils, such as olive oil or vegetable oil.
- Reduce or eliminate trans-fatty acids, found in commercially baked goods such as cookies, crackers, cakes, French fries, onion rings, donuts, processed foods, and margarine.
- Avoid caffeine and other stimulants, alcohol, and tobacco.
- Drink 6 - 8 glasses of filtered water daily.
- Exercise moderately, for 30 minutes daily, 5 days a week.
These specific supplements may help with OA pain:
- Glucosamine/chondroitin, 500 - 1,500 mg daily, for joint health. Results from several well-designed scientific studies suggest that glucosamine supplements may be an effective treatment for OA, particularly OA of the knee or hip. In general, these studies suggest that glucosamine reduces pain, improves function in people with hip or knee OA, reduces joint swelling and stiffness, and provides relief from OA symptoms for up to 3 months after treatment is stopped.
However, the largest clinical trial so far, the 2006 Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT), sponsored by the National Institutes of Health, showed conflicting and somewhat confusing results. The study of about 1,600 people with OA of the knee found that glucosamine and chondroitin did not reduce pain in the overall group, although it did seem to lessen pain among those with moderate-to-severe OA of the knee. The study has raised questions for further research. Researchers are now studying whether the glucosamine-chondroitin combination may in fact help those with more severe OA.
Most studies have shown that glucosamine needs to be taken for 2 - 4 months before it is effective, although you may feel some improvement sooner. Glucosamine and chondroitin can be used along with nonsteroidal anti-inflammatory drugs (NSAIDs) to treat OA.
- Omega-3 fatty acids, such as fish oil, 1 - 2 capsules or 1 tbsp. oil daily, to help decrease inflammation. Higher doses may be used by health care providers.
- SAMe (s-adenosyl-L-methionine), 600 - 1200 mg daily. A number of studies suggest SAMe can help reduce OA pain. In one study, SAMe was as effective in relieving pain as NSAIDs. In another study of people with knee OA, SAMe was as effective as Celebrex in lessening pain and improving joint function, although it took longer to feel the benefits.
- Avocado soybean unsaponifiables (ASUs), 300 - 600 mg daily. A few preliminary studies suggest that this natural vegetable extract may help reduce the symptoms of OA and possible even slow progression of the disease. More research is needed to know whether ASUs can actually stop joint damage.
- Bromelain, 250 mg twice a day. This enzyme that comes from pineapples reduces inflammation. Bromelain may increase the risk of bleeding, so people who take anticoagulants (blood thinners) should not take bromelain without first talking to their doctor. People with peptic ulcers should avoid bromelain. Turmeric is sometimes combined with bromelain, because it makes the effects of bromelain stronger.
Herbs
Herbs are generally available as standardized, dried extracts (pills, capsules, or tablets), teas, or tinctures/liquid extracts (alcohol extraction, unless otherwise noted). Mix liquid extracts with favorite beverage. Dose for teas is 1-2 heaping teaspoonfuls/cup water steeped for 10 - 15 minutes (roots need longer).
- Turmeric (Curcuma longa) standardized extract, 300 mg three times a day, for pain and inflammation. Turmeric is sometimes combined with bromelain, because it makes the effects of bromelain stronger. Turmeric can increase the risk of bleeding, especially for people who take blood-thinnning medications or NSAIDs. Ask your doctor before taking turmeric.
- Cat's claw (Uncaria tomentosa) standardized extract, 30 mg three times a day, has been used traditionally for OA pain. In one study, 100 mg per day of cat’s claw taken for 4 weeks relieved pain better than a placebo. More research is needed. Do not take cat’s claw if you take medicine for high blood pressure or blood-thinning medications.
- Devil's claw (Harpagophytum procumbens) standardized extract, 100 - 200 mg one to two times daily. Devil’s claw has also been used traditionally to relieve pain. One study found that more than 50% of people with OA of the knee or hip or low back pain who took devil’s claw reported less pain and better mobility after 8 weeks. Devil’s claw may increase the risk of bleeding and interact with diabetes medications, so tell your doctor before taking it if you also take blood-thinning medication or if you have diabetes.
- Ginger (Zingiber officinale), up to 2 g per day in divided doses, may reduce joint inflammation and pain. One study found that ginger extract inhibited COX-2, a chemical in the body that causes pain. Ginger may increase the risk of bleeding, so people who take anticoagulants (blood thinners) should not take ginger without first talking to their doctor.
- Willow bark (Salix alba) standardized extract, 500 mg up to three times daily. Willow acts similar to aspirin. Do not take white willow if you are also taking aspirin or blood-thinning medications. Check with your doctor if you are allergic to aspirin or salicylates before taking white willow. Willow should not be given to children under the age of 18.
- Capsaicin (Capsicum frutescens) cream, applied to the skin (topically). Capsaicin is the main component in hot chili peppers (also known as cayenne). Applied to the skin, it is believed to temporarily reduce amounts of “substance P,” a chemical that contributes to inflammation and pain in arthritis. Several clinical studies have shown that capsaicin cream provided better pain relief than a placebo but no improvement in joint swelling, grip strength, or function for people with OA. Pain reduction generally starts 3 - 7 days after applying the capsaicin cream to the skin.
Acupuncture
Several controlled clinical trials suggest that the ancient Chinese practice of acupuncture is an effective treatment for OA pain. It may also help improve joint function. A few clinical studies have found that people with OA experience better pain relief and improvement in function from acupuncture than from NSAIDs such as aspiroxicam.
Chiropractic
Although there is no evidence that chiropractic care can stop joint damage from OA, some clinical studies indicate that spinal manipulation may:
- Increase range of motion
- Restore normal movement of the spine
- Relax the muscles
- Improve joint coordination
- Reduce pain
A review of the scientific literature suggests that chiropractic, especially when combined with glucosamine supplements and stretches and exercise, is an effective supplemental treatment for OA. Chiropractors will avoid using direct thrusts or pressure on red, swollen joints.
Physical Therapy
Physical therapy can improve muscle strength and motion at stiff joints. Physical therapists have many techniques for treating OA.
Manual therapy and supervised exercise may help you put off joint replacement surgery for a time or even avoid it. In one study of people with OA of the knee, those who received manual therapy to the lumbar spine, hip, ankle, and knees showed the following improvements:
- Less stiffness
- Reduced pain
- Improved functional ability
- Improved walking distance
- Less need for knee surgery 1 year later
Balneotherapy (Hydrotherapy or spa therapy)
Balneotherapy is one of the oldest forms of therapy for pain relief for people with arthritis. The term "balneo" comes from the Latin word for bath (balneum) and refers to bathing in thermal or mineral waters. Sulfur-containing mud baths, for example, have been shown to relieve symptoms of arthritis. However, hydrotherapy, which can be performed under the guidance of certain physical therapists, is occasionally used interchangeably with the word balneotherapy. The goals of balneotherapy for arthritis include:
- Improving range of joint motion
- Increasing muscle strength
- Eliminating muscle spasm
- Enhancing functional mobility
- Easing pain
Although balneotherapy is most often used for psoriatic or rheumatoid arthritis, some medical experts believe that it may help people with OA as well. However, one large review of clinical trials found little evidence to support its use.
Ice Massage, Transcutaneous Nerve Stimulation (TENS), and Electroacupuncture
In a well-designed trial comparing the effectiveness of TENS, electroacupuncture, and ice massage for the treatment of knee OA, each of these methods were found to:
- Reduce pain at rest
- Reduce stiffness
- Boost walking speed
- Increase quadriceps muscle strength
- Increase knee range of motion
Many physical therapists use TENS. When the nerve stimulation of TENS is applied to acupuncture points, it is called electroacupuncture.
Mechanical Aids (braces, splints)
Many mechanical devices, called orthoses, are available for people with OA to help support and protect joints. Made from lightweight metal leather, elastic, foam, and plastic, they allow some movement of the affected joint while not restricting nearby joints. For example, splints or braces help align joints and properly distribute weight. Shock-absorbing soles in shoes can help in daily activities and during exercise. Physical therapists use these mechanical aids most frequently to treat hands, wrists, knees, ankles, and feet. Orthoses should be custom-fitted by a physical or occupational therapist.
Homeopathy
Although very few studies have examined the effectiveness of specific homeopathic therapies, professional homeopaths may consider the following treatments to alleviate symptoms of OA based on their knowledge and experience. Before prescribing a remedy, homeopaths take into account a person's constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
Although people with OA are best treated with an individualized homeopathic remedy chosen by a professional homeopath, several trials have found that some common homeopathic combinations may be at least as effective as conventional medications for OA. Potential remedies include:
- A topical homeopathic gel containing comfrey (Symphytum officinale), poison ivy (Rhus toxicodendron), and marsh-tea (Ledum palustre)
- A combination homeopathic preparation containing R. toxicodendron., Arnica montana (arnica), Solanum dulcamara (climbing nightshade), Sanguinarra canadensis (bloodroot), and Sulphur
- A liquid homeopathic preparation containing R. toxicodendron, Causticum (potassium hydrate), and Lac vaccinum (cow's milk)
Other Common Homeopathic Remedies for OA Include:
- Calcarea carbonica (carbonate of lime or calcium carbonate)
- Bryonia (wild hops)
- Graphites
- Guaiacum
Mind-Body Medicine
Chronic pain and disability can make daily life difficult. Treating the whole person and paying attention to the mind as well as the body can improve quality of life. Many people report that relaxation techniques, such as guided imagery and meditation, are an important part of their care, and help to reduce pain and other symptoms of OA.
Yoga
This ancient Indian practice is well known for its physical, psychological, emotional, and spiritual benefits. In the West, it is often recommended to relieve musculoskeletal symptoms and some studies have found it can help relieve OA pain. In one clinical trial studying OA of the hand, the group practicing yoga showed significantly less pain and improved range of motion compared to those participating in non-yoga stretching and strengthening sessions. Some yoga "asanas" (postures) strengthen the quadriceps and emphasize stretching, both of which help people with OA of the knee. People with arthritis should begin asanas slowly and they should be performed only after a warm up. Look for a reputable instructor who knows how to modify postures for people with arthritis.
Tai Chi
This ancient form of classical conditioning has been practiced in China for centuries. Like yoga, it is sometimes recommended to help relieve arthritis pain. Clinical studies have found the following benefits of tai chi:
- Improved fitness
- Stronger muscles
- Better flexibility
- Reduced percentage of body fat
- Lowered risk of falls in the elderly
In a clinical trial of people with OA of the knee or hip (ranging in age from 49 - 81), those who practiced tai chi twice a week for 3 months showed significant improvement compared to those in the control group. Improvement was seen in the following areas:
- Overall sense of quality of life
- Fewer feelings of stress/tension
- More satisfaction with general health
- Less fatigue
- Easier self management of arthritis symptoms
Other Considerations
Pregnancy
Many of the herbs used in treatment for OA have not been tested on pregnant women and some are known to be unsafe in pregnancy. You should not take any medication, herb, or supplement when you are pregnant without first talking to your obstetrician.
Prognosis and Complications
Complications of OA include:
- Inability to walk due to very advanced hip or knee OA
- Gastrointestinal bleeding and decreased kidney function resulting from long-term NSAID use
Many people are able to control OA and prevent the condition from getting worse over time. Knee OA is still the No. 1 cause of disability in countries such as the United States. In the most advanced stages, OA can cause complete cartilage loss. In some cases joint replacement may be necessary. While OA can be a debilitating condition, current treatments have shown great promise in reducing pain and improving mobility.
Rheumatoid arthritis (RA) is an autoimmune disease where the body’s immune system mistakenly attacks the synovium, a thin membrane that lines the joints. It causes chronic inflammation that leads to pain, swelling, and stiffness. Eventually, bones and joints can be damaged, leading to disability.
RA usually affects joints on both sides of the body equally -- if a joint on one side is affected, the same joint on the opposite side if affected. Wrists, fingers, knees, feet, and ankles, and elbows are most often affected. RA can also affect other organs, and people who have RA are at higher risk for other diseases including heart disease, diabetes, and osteoporosis.
RA is a chronic disease, and it is important that people with RA work closely with their doctor .to find a treatment plan that lessens symptoms and joint damage.
There is no cure for RA, but taking medication and making lifestyle changes can help you manage the disease. Alternative and complementary therapies can also help relieve symptoms, but only conventional medications can halt the progression of the disease and stop further joint damage. In some cases, medications can help put RA into remission and symptoms may disappear completely.
Signs and Symptoms
Symptoms of RA include:
- Morning stiffness -- waking up with stiff joints (often the wrists and base of the fingers, ankles, balls of the feet, elbows, or knees)
- Joint pain with warmth, swelling, tenderness, and stiffness of the joint after resting
- Limited range of motion in the affected joints
- Fatigue
- Low grade fever (when having a flare)
- Small, round, firm bumps (called nodules) under the skin; you can feel these, but they are generally painless.
Causes
The cause of RA isn’t known, although genetics and environment probably play a part. Researchers believe that genetics may predispose some people to RA. In those people, environmental factors, bacteria, and viruses may then trigger RA. Some evidence suggests that hormones may also play a role, but researchers aren’t sure.
In RA, the body’s immune system -- which normally fights off foreign invaders -- mistakenly attacks the lining of the joints (called the synovium). That causes inflammation, which thickens the synovium and eventually destroys the cartilage and bone in the joints.
RA can occur at any age. It usually occurs in people between 25 - 55 years of age. Women are affected more often than men.
RA usually affects joints on both sides of the body equally. Wrists, fingers, knees, feet, elbows, and ankles are the most often affected.
Risk Factors
- Age. Although the disease can occur at any age, RA generally starts in young adulthood usually between ages 25 and 55.
- Gender. Women get RA two and a half times more often than men, and are more likely to have severe symptoms.
- Family history. Having relatives with RA increases your risk of getting it yourself.
- Cigarette smoking. Smoking seems to increases your risk of getting RA.
- Medication. Interferon-alpha, a drug used to treat hepatitis, autoimmune diseases, and other diseases has triggered RA in rare cases
Diagnosis
RA can be hard to diagnose because it resembles many other conditions, and symptoms may develop so gradually. Even after RA has been diagnosed, it is extremely important to determine how the disease is progressing in order to treat it appropriately.
Your doctor will take your medical history and do a physical exam. Blood tests, x-rays, and aspiration (the removal of fluid from the joint) may also be needed. Several blood tests may be done. One test checks for an elevated erythrocyte sedimentation rate (ESR, or sed rate), which is a sign of inflammation in the body. Other blood tests that may be done include checking for certain antibodies, including rheumatoid factor, antinuclear antibodies (ANA), and anti-cyclic citrullinated peptide (anti-CCP) antibodies. These antibodies are present in most people with RA, but not all.
Treatment Approach
If you have RA, it is important to get it diagnosed and start treatment early. Studies have shown that early, aggressive treatment for RA can halt the destruction of joints. In addition to rest, regular exercise, and taking anti-inflammatory medications, your doctor will start you on disease-modifying anti-rheumatic drugs (DMARDs). These drugs do more than relieve symptoms -- they halt the progression of the disease.
Complementary and alternative therapies can be used along with conventional treatment to help relieve pain and stiffness. Studies show that certain dietary supplements, particularly omega-3 fatty acids, show promise in helping to relieve symptoms. Be sure to tell all your health care providers about any supplements, herbs, or other therapies you are using. Some herbs and supplements can interact with certain medications and should not be taken together.
RA usually requires lifelong treatment, including medications, physical therapy, education, and possibly surgery. Frequently, the disease can be controlled with a combination of treatments.
Lifestyle
Regular exercise -- consisting of aerobic exercise, strengthening exercises, and flexibility or range of motion exercises -- prescribed by a physical therapist can help to maintain joint motion and strength. Exercise also helps relieve pain and helps you maintain a proper weight, which takes pressure off your joints.
Doctors often recommend walking, swimming, warm-water exercise, or biking for people with RA. If you are not used to exercising, start slow and work your way up, aiming for 30 minutes of aerobic exercise 5 or more days a week.
Weight-bearing exercises (such as lifting weights, using a resistance band, or walking) are also recommended to keep bones strong. People with RA often take corticosteroids to reduce inflammation. Taking corticosteroids long-term raises the risk of developing osteoporosis.
Joint protection techniques, such as heat and cold treatments and splints or orthotic (straightening) devices to support and align joints, may help as well.
Nutrition and Dietary Supplements
For anyone with a chronic illness, eating a healthy diet that’s low in saturated fat and high in antioxidant foods -- fruits and vegetables -- is essential. Eating foods that are high in saturated fat may contribute to inflammation in the body.
Also, people with RA are at higher risk of developing heart disease and diabetes. A healthy diet and regular exercise can lower that risk.
Although diet cannot cure RA, some people report that they have less pain, stiffness, and fatigue when they switched from a typical Western diet (high in animal protein and simple sugars) to a vegan diet with lots of uncooked berries, fruits, vegetables, nuts, roots, seeds, and sprouts. Vegan diets contain no animal products and get protein from vegetable sources.
Some people think food allergies may play a part in the inflammation common in RA, and say that their symptoms get worse after they eat certain foods. Although researchers aren’t sure if food allergies are to blame, you may want to try an elimination diet, which removes certain foods from your diet and then adds them back in, one by one. You will need to keep careful track of your symptoms in a food diary. Usually it’s best to try an elimination diet under the supervision of your doctor or a registered dietitian.
These general nutritional tips can help you eat a healthy diet:
- Avoid refined foods such as white breads, pastas, and sugar.
- Eat fewer red meats and more lean meats, cold-water fish, tofu (soy, if no allergy) or beans for protein.
- Use healthy cooking oils, such as olive oil or vegetable oil.
- Reduce or eliminate trans-fatty acids, found in commercially baked goods such as cookies, crackers, cakes, French fries, onion rings, donuts, processed foods, and margarine.
- Avoid caffeine and other stimulants, alcohol, and tobacco.
- Drink 6 - 8 glasses of filtered water daily.
- Exercise 30 minutes daily, 5 days a week.
These supplements may help relieve inflammation and pain:
- Omega-3 fatty acids, such as fish oil, up to 2.6 g daily -- Omega-3 fatty acids may help reduce inflammation. A review of studies where people with RA took omega-3 fatty acids found they had fewer tender joints but no difference in joint damage. In some studies, people who take omega-3s are able to reduce the dose of NSAIDs or corticosteroids they take for RA. Omega-3 fatty acids may also reduce the risk of heart disease, which is elevated in people with RA. Omega-3 fatty acid supplements may raise the risk of bleeding, so ask your doctor if they are right for you.
- Vitamin E -- One study suggests that taking vitamin E along with standard medications for rheumatoid arthritis may help reduce pain -- but not inflammation -- better than standard medications alone.
- Bromelain (500 mg - 2,000 mg three times daily) -- This enzyme derived from pineapples may help reduce inflammation and pain. It may increase the risk of bleeding, so ask your doctor before taking it.
- Gamma linolenic acid (GLA), found in borage oil, evening primrose oil, and black currant seed oil, 1.1 g - 2.6 g daily -- may help reduce pain, stiffness, and swelling. One study found that people with RA who took 2.8 g of GLA for six months reduced pain and swelling and improved their grip strength.
- Folic acid -- People who take methotrexate for RA may need additional folic acid, because methotrexate hinders the body’s ability to absorb folic acid. In addition, one study found that folic acid supplements helped reduce side effects (including liver problems) from methotrexate. High doses of folic acid can mask a vitamin B-12 deficiency, so ask your doctor if you need folic acid supplements -- don’t just start taking them on your own.
Herbs
You can use herbs in the form of dried extracts (capsules, powders, teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, make teas with 1 tsp. herb per cup of hot water. Steep covered 5 - 10 minutes for leaf or flowers, and 10 - 20 minutes for roots. Drink 2 - 4 cups per day.
Herbs may be a helpful addition to conventional treatment for RA, but should never be used alone to treat RA. Herbs do not halt joint damage and progression of the disease, as some conventional medications can.
- Boswellia (Boswellia serrata), 400 mg - 800 mg three times daily -- Boswellia has been used traditionally to treat arthritis in Ayurvedic medicine. Studies using it to treat RA have been mixed. Some found that it relieved pain and swelling, but others found it was no better than placebo.
- Ginger (Zingiber officinale), up to 2 g per day in divided doses, may reduce joint inflammation and pain. One study found that ginger extract inhibited COX-2, a chemical in the body that causes pain. Ginger may increase the risk of bleeding, so people who take anticoagulants (blood thinners) should not take ginger without first talking to their doctor.
- Green tea (Camelia sinensis) standardized extract, 250 - 500 mg daily -- Green tea is loaded with antioxidants, and test tube studies found that it may block inflammatory chemicals that are involved in RA. Use caffeine-free products. You may also prepare teas from the leaf of this herb.
- Cat's claw (Uncaria tomentosa) standardized extract, 20 mg three times a day -- may help reduce inflammation. One study found that people with RA who took cat’s claw experienced a modest reduction in pain and swelling. Cat’s claw may stimulate the immune system, which could cause problems in a disease like RA where the immune system is already overactive. For that reason, do not take cat’s claw except without the supervision of your doctor.
- Turmeric (Curcuma longa) standardized extract, 400 mg three times a day -- may help reduce pain and inflammation. It is sometimes combined with bromelain, because it makes the effects of bromelain stronger. Turmeric can increase the risk of bleeding, so ask your doctor before taking it.
- Devil's claw (Harpagophytum procumbens) standardized extract, 100 - 200 mg one to two times daily -- may reduce inflammation. One study found that people with RA who took devil’s claw reduced pain and improved their mobility. But not all studies have found that devil’s claw was effective for RA; evidence is mixed.
- Capsaicin (Capsicum frutescens) cream, applied to the skin (topically) -- Capsaicin is the main component in hot chili peppers (also known as cayenne). Applied to the skin, it is believed to temporarily reduce amounts of “substance P,” a chemical that contributes to inflammation and pain in arthritis. Pain reduction generally starts 3 - 7 days after applying the capsaicin cream to the skin. Wash hands well with vinegar after use and avoid touching the eyes.
Acupuncture
There is little to no scientific evidence supporting the use of acupuncture for RA. However, some people with RA report that acupuncture helps relieve their pain and improves their quality of life. Acupuncturists treat people with RA based on an individualized assessment of the excesses and deficiencies of qi, or energy, located in various meridians. A qi deficiency is usually detected in the spleen and kidney meridians.
Acupuncturists may use moxibustion (a technique in which the herb mugwort is burned over specific acupuncture points) to strengthen the entire energy system. Qualified acupuncturists may also provide lifestyle, dietary, and herbal advice to people with RA. Practitioners may apply local treatment to the painful areas and related sore points, either with a needle or moxibustion. You should not rely on acupuncture alone to treat RA, as it does not halt progression of the disease. It may be helpful as a supportive treatment with conventional medical therapy.
Exercise
Regular exercise is important for people with RA. It boosts overall health, helps you maintain a proper weight (which takes pressure off joints), and helps prevent heart disease, diabetes, and osteoporosis. It also reduces pain and can improve mood.
While you may choose to rest during an active flare, it’s important to stay in good shape and maintain range of motion in your joints. Ask your doctor or physical therapist to design an exercise program for you. Many people with RA find that walking, swimming, or warm-water exercise are helpful.
Doctors used to advise people with RA do only gentle exercises, fearing more joint damage. But recent research suggests that more intense exercise may not only be safe, but may actually produce greater muscle strength and overall functioning. To know how long or hard you should exercise, ask your doctor and pay attention to signs from your body:
If you feel sharp pains while exercising, stop immediately.
Some soreness after exercising is normal. If aches and pains continue for more than 2 hours afterwards, try a lighter exercise program for a while.
Be sure to warm up and cool down.
Using large joints instead of small ones for ordinary tasks can help relieve pain. For example, use your hip to close doors or the palm of your hand to push buttons.
Balneotherapy (Hydrotherapy or spa therapy)
Balneotherapy is one of the oldest forms of therapy for pain relief for people with arthritis. The term "balneo" comes from the Latin word for bath (balneum) and refers to bathing in thermal or mineral waters. For example, sulfur-containing mud baths have been shown to relieve symptoms of arthritis. The goals of balneotherapy for arthritis include:
- Improving range of joint motion
- Increasing muscle strength
- Eliminating muscle spasm
- Enhancing functional mobility
- Easing pain
Exercising and swimming in a heated pool may also help.
Mechanical Aids
A variety of mechanical devices, called orthoses, are available for people with RA to help support and protect joints. Made from lightweight metal leather, elastic, foam, and plastic, they allow some movement of the affected joint while not restricting nearby joints. For example, splints or braces help align joints and properly distribute weight. Shock-absorbing soles in shoes can help in daily activities and during exercise. Physical therapists use these mechanical aids most frequently to treat hands, wrists, knees, ankles, and feet. Orthoses should be custom-fitted by a physical or occupational therapist.
Compression gloves may help some people. Two studies on the overnight use of compression gloves (close-fitting nylon-spandex gloves) concluded that the gloves reduced pain and stiffness in people with RA in the fingers.
Other possibilities for symptom relief include:
- Transcutaneous nerve stimulation (TENS) -- small clinical studies show that TENS, a technique used by many physical therapists, may provide short-term pain relief for people with RA.
- Heat and cold applications -- may reduce pain
Homeopathy
Recent trials evaluating homeopathy to treat RA found that the remedies were no better than placebo in reducing symptoms. These studies contradict an older trial that showed positive effects with homeopathic treatment. Despite the lack of definitive evidence, professional homeopaths might recommend one of the following treatments for RA based on their knowledge and clinical experience. Before prescribing a remedy, homeopaths take into account an individual's constitutional type -- your physical, emotional, and intellectual makeup. An experienced homeopath assesses all of these factors when determining the most appropriate remedy for a particular individual.
Potential remedies include:
- A topical homeopathic gel containing comfrey (Symphytum officinale), poison ivy (Rhus toxicodendron), and marsh-tea (Ledum palustre)
- A combination homeopathic preparation containing R. toxicodendron, Arnica montana (arnica), Solanum dulcamara (climbing nightshade), Sanguinarra canadensis (bloodroot), and Sulphur
- A liquid homeopathic preparation containing R. toxicodendron, Causticum (potassium hydrate), and Lac vaccinum (cow's milk)
Mind-Body Medicine
Chronic pain and disability can make daily life difficult, and stress can make an RA flare worse. Many people report that relaxation techniques, such as guided imagery and meditation, help improve quality of life and reduce pain and other symptoms of RA.
Yoga
This ancient Indian practice is well known for its physical, psychological, emotional, and spiritual benefits. In the West, it is often recommended to relieve musculoskeletal symptoms and some studies have found it can help relieve RA pain. Some yoga "asanas" (postures) strengthen the quadriceps and emphasize stretching, both of which help people with RA of the knee. People with arthritis should begin asanas slowly and they should be performed only after a warm up. Look for a reputable instructor who knows how to modify postures for people with RA.
Tai Chi
This gentle exercise program practiced in China for centuries has been shown to produce a number of benefits, including the following:
- Better fitness
- Increased muscular strength
- Better flexibility
- Reduced percentage of body fat
- Reduced risk of falls in the elderly
Tai chi is generally safe for people with RA, and a review of scientific studies has found that it may help improve flexibility and range of motion, especially for people with RA in their ankles.
Other Considerations
Prognosis and Complications
RA is associated with many complications.
- Joint deformities
- Cervical spine problems (can be life threatening)
- Painless, hard, round or oval masses called nodules that appear under the skin
- Pleuritis (inflammation of the lungs)
- Anemia
- Rheumatoid vasculitis (inflammation of the blood vessels)
- Pericarditis (inflammation of the outer lining of the heart)
- Myocarditis (inflammation of the heart muscle)
- Heart failure
- Eye inflammation
- Osteoporosis
- Heart disease
- Diabetes
The course of the disease varies between people. People with a certain antibody in the blood (anti-CCP) or nodules may be at risk for faster progression of the disease. People who develop RA at younger ages also tend to have faster disease progression.
Although complications may shorten the life expectancy of people with RA, treatment is constantly improving and newer medications offer more hope for remission.
Asthma
Asthma is a chronic disease that involves inflammation of the lungs. Airways swell and restrict airflow in and out of the lungs, making it hard to breathe. The word asthma comes from the Greek word for "panting." People with asthma pant and wheeze because of the restricted flow of air.
Normally, when you breathe in an irritant or are you experience a stressful activity such as exercise, your airways relax and open. This allows the lungs to get rid of irritants or take in more air. But with asthma, muscles in the airways tighten, and the lining of the air passages swells.
About 20 million Americans have asthma, including 9 million children. In fact, asthma is the most common chronic childhood illness. About half of all cases develop before the age of 10, and many children with asthma also have allergies.
Asthma can either be allergic or non-allergic. In allergic asthma, an allergic reaction to an inhaled irritant -- pet dander, pollen, dust mites -- triggers an attack. The immune system springs into action, but instead of helping, it causes inflammation. This is the most common form of asthma.
Non-allergic asthma does not involve the immune system. Attacks can be triggered by stress, anxiety, cold air, smoke, or a virus. Some people have symptoms only when they exercise, a condition known as exercise-induced asthma.
While there is no cure for asthma, it can be controlled.
Signs and Symptoms
Most people with asthma may go for periods of time without any symptoms, then experience an asthma attack. Some people experience chronic shortness of breath that gets worse during an attack. Asthma attacks can last minutes to days, and can become dangerous if airflow to the lungs becomes severely restricted.
Primary symptoms include:
- Shortness of breath
- Wheezing -- usually begins suddenly; may be worse at night or early in the morning; can be made worse by cold air, exercise, and heartburn; is relieved by using bronchodilators (drugs that open the airways; see Medications)
- Chest tightness
- Cough (dry or with sputum) -- in cough-variant asthma, this may be the only symptom
If you have any of these symptoms, seek emergency treatment:
- Extreme difficulty breathing or stopping breathing
- Bluish color to the lips and face (called cyanosis)
- Severe anxiety
- Rapid pulse
- Excessive sweating
- Decreased level of consciousness (such as drowsiness or confusion)
Causes
Asthma is most likely caused by several factors. Genes play a part; you’re more likely to develop asthma if others in your family have it. Among those who are susceptible, being exposed to environmental factors such as allergens (substances that cause an allergic reaction) or infections may increase the chance of developing asthma.
Risk Factors
The following factors may increase the risk of developing asthma:
- Having allergies
- Family history of asthma or allergies
- Being exposed to secondhand smoke
- Having upper respiratory infections as an infant
- Living in a large city
- Gender -- among younger children, asthma develops twice as often in boys as in girls, but after puberty it may be more common in girls
- Obesity
- Gastroesophageal reflux (heartburn)
Triggers
Childhood asthma, in particular, can be triggered by almost all of the same things that trigger allergies, such as:
- Sensitivity to allergens such as dust, cockroach waste, pet dander, indoor and outdoor mold, pollen
- Air pollutants, such as smoke, perfumes, diesel particles, sulfur dioxide, high ozone levels, and fumes from paint, cleaning products, and gas stoves
- Changes in the weather, especially in temperature (particularly cold) and humidity
Other triggers include:
- Activities that affect breathing (exercising, laughing, crying, yelling)
- Stress and anxiety
Diagnosis
Asthma symptoms can mimic several other conditions, and your doctor will take a thorough history to rule out other diseases. You may also have lung function tests to measure how much air your lungs can hold and how much air you breathe out. Your doctor may use a spirometer to measure how much air you exhale and how quickly you get air out of your lungs. Other tests may include chest and sinus x-rays, blood tests, or allergy tests.
Asthma is classified as
- Mild intermittent: Having mild symptoms up to 2 days a week and 2 nights a month
- Mild persistent: Having symptoms more than 2 a week but not more than one time in a single day
- Moderate persistent: Having symptoms once a day and more than one night per week
- Severe persistent: Having symptoms throughout the day on most days and often at night.
Although you can’t prevent asthma, you can take several steps to reduce the number and frequency of attacks:
- Avoid allergens and irritants as much as possible. For example, reduce your exposure to dust mites by using special mattress and pillow covers that keep allergens out and removing carpets from bedrooms. Clean your house frequently.
- Exercise. Even people with exercise-induced asthma can stay active, and exercise will help you by strengthening your lungs and helping you maintain a proper weight. Taking precautions when it’s cold outside -- such as wearing a face mask to warm the air that you’re breathing -- can help you avoid asthma symptoms. Talk to your doctor before starting an exercise regimen.
- Pay attention to your breathing. Watch for signs of an oncoming attack, such as wheezing. Your doctor may give you a machine called a peak flow meter that can detect slight differences in your breathing before you even notice them, so that you can take medication to ward off an attack.
- Treat attacks quickly. The sooner you treat an attack, the less severe it will be, and the less medication you’ll need.
If you have allergies, immunotherapy (“allergy shots”) may lower the number of asthma attacks and their intensity, and reduce the amount of medication you need. Immunotherapy includes regular injections of an allergen (the substance that’s causing the allergic reaction), with each shot containing a slightly higher amount. Over time your immune system becomes used to the allergen and no longer reacts to it. Talk to your doctor about whether immunotherapy is right for you.
Treatment
Avoiding asthma attacks, reducing inflammation, and preventing lung damage are the primary goals of treatment. The more you know about your condition, the more closely you can work with your doctor to develop a treatment plan. To control asthma, you need to prevent exposure to allergens or irritants and take medication as prescribed. You may need emergency medications during an asthma attack, but monitoring your breathing and taking your medications every day will help you control asthma over the long term.
Severe attacks may require hospitalization for oxygen and medications that are given intravenously (IV).
Lifestyle
If you smoke, quit.
Lose weight if you are overweight. Being overweight may put pressure on the lungs and trigger an inflammatory response.
Monitor your condition every day using a peak flow meter (a portable device that helps measure how your lungs are working). Keep a diary of readings to show your doctor; together, you will establish your "personal best" reading. You should call your doctor if your peak flow reading falls below 80% of your personal best and go to the hospital if it falls below 50%.
Keep a journal that logs changes or attacks -- it may help determine triggers.
Nutrition and Dietary Supplements
Although asthma cannot be cured by any nutritional supplement, people who have a chronic illness such as asthma should eat well-balanced meals that include plenty of fruits and vegetables. Some studies have shown that people with asthma tend to have low levels of certain nutrients, but there is no evidence that taking supplements helps reduce asthma attacks. However, an overall healthy diet will ensure you get the nutrients you need and help your body deal with a long-term condition such as asthma.
- Choline (3 g per day) -- Choline, a B vitamin, may help reduce the severity and frequency of asthma attacks.. Some evidence indicates that higher doses (3 g per day) may be most effective. More research is needed to say for sure whether choline helps.
- Magnesium -- The idea of using magnesium to treat asthma comes from the fact that people who have asthma often have low levels of magnesium, and from some (but not all) studies showing that intravenous (IV) magnesium can be effective as an emergency treatment for an asthma attack. However, studies that have looked at whether taking oral magnesium helped have shown mixed results. More research is needed.
- Omega-3 fatty acids -- The evidence for using omega-3 fatty acids (found in fish oil) to treat asthma is mixed. At least a few studies have found that fish oil supplements may reduce inflammation and symptoms in children and adults with asthma. But the studies have only included a small number of people, and one study found that fish oil might make aspirin-induced asthma worse. Ask your doctor whether a high quality fish oil supplement makes sense for you.
- Quercetin -- Quercetin, a kind of antioxidant called a flavonoid, stops the production and release of histamine and other allergic/inflammatory chemicals in the body. Histamine contributes to allergy symptoms such as a runny nose, watery eyes, and hives. Because of that, quercetin has been proposed as a treatment for asthma. But no human studies have examined whether it works or not.
- Selenium -- Studies suggest that people with asthma tend to have low levels of selenium. In addition, a population-based study suggested that eating selenium-rich foods may reduce the risk of asthma. And in one small study of 24 people with asthma, those who received selenium supplements for 14 weeks had fewer symptoms than those who received placebo. However, another study indicated that people who took 200 mcg of selenium per day for about eight years were more likely to develop type 2 diabetes. You should not take selenium supplements without first talking to your doctor.
- Vitamin C (1 g per day) -- One preliminary study suggested that children with asthma had significantly less wheezing when they ate a diet rich in fruits with vitamin C. Vitamin C does have anti-inflammatory and antioxidant properties, which may help you maintain good health overall. Some studies have indicated that taking a vitamin C supplement (1 g per day) may help keep airways open, but other studies have found no benefit.
- Other -- Other supplements that may help treat asthma include:
- Coenzyme Q 10 (CoQ10) -- if you have asthma, you may have low levels of this antioxidant in your blood. Researchers don’t know, however, whether taking CoQ10 supplements will make any difference in your symptoms.
- Lycopene and beta-carotene -- preliminary data suggests that these two antioxidants, found in many fruits and vegetables, may help prevent exercise-induced asthma.
- Vitamin B6 -- may be needed if you are taking theophylline because this medication can lower blood levels of B6.
- Potassium -- levels in the body also may be lowered if you take theophylline.
Herbs
The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and interact with other herbs, supplements, or medications. For these reasons, herbs should be taken with care, under the supervision of a health care practitioner.
- Boswellia (Boswellia serrata, 3 mg three times per day) -- Boswellia (also known as Salai guggal), an herb commonly used in Ayurvedic medicine (a traditional Indian system of health care), has shown promise in treating asthma. In one double-blind, placebo-controlled study, people who took boswellia had fewer attacks and improved lung function. Boswellia may help leukotreine modifiers work better. However, more research is needed. People who take medication to lower their cholesterol, or people who take nonsteroidal anti-inflammatory drugs (NSAIDs) should talk to their doctor before taking boswellia.
- Coleus forskohlii -- Coleus forskohlii is another herb used in Ayurvedic medicine to treat asthma. A few preliminary studies suggest that inhaled coleus powder seemed to relieve symptoms, but more research is needed to know for sure. People who have diabetes or thyroid conditions should not take coleus. If you take an anticoagulant (blood thinner), taking coleus may increase your risk of bleeding. Pregnant women should not take coleus.
- Tylophora (Tylophora indica, 250 mg one to three times per day) -- Tylophora has also been used historically to treat asthma. Some modern scientific studies show that it can help reduce symptoms, but the studies were not the best quality. More research is needed. Tylophora may cause serious side effects at high doses, so talk to your doctor before taking it. Do not take tylophora if you are pregnant, have diabetes, high blood pressure, or congestive heart failure.
- Pycnogenol (Pinus pinaster, 1 mg per pound of body weight, up to 200 mg) -- A 2002 review of studies on a standardized extract from French maritime pine bark, called pycnogenol, suggests that it may reduce symptoms and improve lung function in people with asthma. Do not use pycnogenol if you have diabetes or take medication for high blood pressure. Taking pycnogenol with an anticoagulant (blood thinner) -- including aspirin -- can increase your risk of bleeding; talk to your doctor first.
- Saiboku-to -- A traditional Japanese herbal mixture called Saiboku-to has helped reduce symptoms and allowed study participants to reduce doses of corticosteroids in three preliminary trials. In test tubes, Saiboku-to has shown anti-inflammatory effects. Saiboku-to contains several herbs, including Asian ginseng (Panax ginseng), Chinese skullcap (Baikal scutellaria), licorice (Glycyrrhiza glabra), and ginger (Zingiber officinale). Talk to your healthcare provider before taking Saiboku-to as the herbs it contains can interact with other herbs and medications.
Acupuncture
Some preliminary studies indicate that acupuncture may help reduce symptoms for some people with asthma, but not all studies agree. It is important to note that acupuncture should be used in addition to, not as a replacement for, conventional medicine when treating asthma.
Homeopathy
Although very few studies have examined the effectiveness of specific homeopathic therapies, professional homeopaths may consider the following remedies for the treatment of asthma based on their knowledge and experience. Before prescribing a remedy, homeopaths take into account a person's constitutional type-- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
- Arsenicum album -- for asthma that generally worsens between midnight and 2 am and is accompanied by restlessness, anxiety, chills, and thirst.
- Ipecacuanha -- for those with asthma, particularly children, who have significant tightness in the chest, a chronic cough with lots of phlegm that may lead to vomiting, and worsening of symptoms in hot, humid weather.
- Pulsatilla -- for asthma with yellow or greenish phlegm that gets worse in the evening, in warm, stuffy rooms, or after consuming rich, fatty foods; this remedy is most appropriate for adults or children who are tearful and clingy or sweet and affectionate.
- Sambucus -- for asthma that awakens a person at night with a sensation of suffocation; symptoms worsen when the person is lying down .
Mind-Body Medicine
Because stress and anxiety can make asthma worse, including stress management techniques in your daily life may help reduce symptoms. These techniques do not directly treat asthma, however.
- Hypnosis -- may be especially useful for children, who can readily learn the technique.
- Yoga -- in addition to general relaxation and stress reduction, several studies of people with asthma have suggested that lung function improve with the regular practice of yoga. Any benefits in breathing appear to be slight, however.
- Journaling -- A study published in the New England Journal of Medicine documented the positive effect of daily journaling on people with asthma. Some people think that journaling allows for the release of pent-up emotions and helps reduce stress overall.
Other Considerations
Warnings and Precautions
Long-term treatment with theophylline for asthma may reduce blood levels of vitamin B6.
Prognosis and Complications
People with asthma can live normal, active lives. Because asthma is a chronic illness, it requires self-care and monitoring over the long term, as well as close contact with your doctor. Most people with asthma have occasional attacks separated by symptom-free periods. Paying attention to your mood, lowering the stress in your life, and having a good emotional support system will help you take good care of yourself.
Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by inattention, hyperactivity, and impulsivity. It is the most commonly diagnosed behavioral disorder of childhood, affecting between 3 - 5% of school-aged children. Although many people sometimes have difficulty sitting still, paying attention, or controlling impulsive behavior, people with ADHD find that these symptoms greatly interfere with everyday life. Generally, these symptoms appear before age 7 and can lead to problems in school and in social settings. One- to two-thirds of all children with ADHD continue to have symptoms when they grow up. A diagnosis can be controversial, since there are no lab tests for ADHD and no objective way to measure a child's behavior. Some experts also disagree about the best way to treat ADHD, but taking action early can improve a child's educational and social development.
Signs and Symptoms
A person is considered to have ADHD if they have at least 6 symptoms from the following categories, lasting for at least 2 months. In diagnosing children, the symptoms must appear before age 7 and pose a significant challenge to everyday functioning in at least two areas of life (usually home and school). Most children do not show all the symptoms, and they may be different in boys and girls (boys may be more hyperactive and girls more inattentive).
Inattention
- Fails to pay close attention to details or makes careless mistakes
- Has difficulty sustaining attention in tasks or play activities
- Does not seem to listen when spoken to directly
- Does not follow through on instructions and fails to finish tasks
- Has difficulty organizing tasks and activities
- Avoids, dislikes, or is reluctant to engage in tasks that require sustained mental effort (such as school work, homework)
- Loses things needed for tasks or activities
- Is easily distracted
- Is forgetful in daily activities
Hyperactivity and Impulsivity
- Fidgets with hands or feet or squirms in seat
- Does not remain seated when expected to
- Runs or climbs excessively in inappropriate situations (in teens or adults, may be feelings of restlessness)
- Has difficulty playing or engaging in leisure activities quietly
- Acts as if "driven by a motor"
- Talks excessively
- Blurts out answers before questions are completed
- Has difficulty waiting his or her turn
- Interrupts or intrudes on others
What Causes It?
No one is sure what causes ADHD. Although environment may play a role, researchers are now looking to find answers in the structure of the brain.
- Altered brain function -- Brain scans have shown differences in the brains of ADHD children compared to those of non-ADHD children. For example, many children with ADHD tend to have altered brain activity in the prefrontal cortex, a part of the brain thought to be the command center. This may affect their ability to control impulsive and hyperactive behaviors. Researchers also believe hyperactive behavior in children can be caused by too much slow-wave (or theta) activity in certain regions of the brain.
- Genetics -- ADHD seems to run in families.
- Maternal or childhood exposure to certain toxins -- Women who smoke, drink, and are exposed to PCBs during pregnancy are more likely to have children with ADHD. Children who are exposed to lead or PCBs are more likely to develop the disorder.
Risk Factors
Risk factors for ADHD include:
- Heredity -- children with ADHD usually have at least one first-degree relative who also has the disorder.
- Gender -- ADHD is four to nine times more common in boys than in girls. Some experts believe that the disorder is underdiagnosed in girls, however.
- Prenatal and early postnatal health -- maternal drug, alcohol, and cigarette use; exposure of the fetus or infant to toxins, including lead and PCBs; nutritional deficiencies and imbalances.
- Other behavioral disorders, especially those that involve too much aggression (such as oppositional defiant or conduct disorder).
What to Expect at Your Provider's Office
Because there is no objective test for ADHD, making a diagnosis can be hard. A number of tests and observations may be used. For this reason, it is crucial to make sure the doctor who evaluates you or your child has training in diagnosing ADHD.
To evaluate a child, the doctor will take a complete medical history and do a thorough exam to check for conditions that may mimic ADHD, such as hyperthyroidism or problems with vision, hearing, and sleeping. Because many symptoms show up at home or school rather than the doctor's office, you may be asked to fill out questionnaires. Your child's teacher may be interviewed. Your doctor will try to determine not only how the child behaves but also where the behavior occurs and how long it lasts. Children with ADHD have long-lasting symptoms that usually show up during stressful situations or situations that require sustained attention (such as schoolwork).
Diagnosing an adult with ADHD can be even more challenging. Because your symptoms would have appeared when you were young, your doctor may try to find out as much as possible about you when you were a child by getting information from your parents or former teachers. (If your symptoms are recent, you are not considered to have adult ADHD.) In addition to ruling out the other conditions mentioned above, your doctor may also check for depression and bipolar disorder, which can mimic ADHD.
Preventive Care
Because the cause or causes of ADHD are not known, there is no way to prevent the condition. It can be managed with medication, behavioral therapy, and lifestyle changes.
Treatment Options
How to treat ADHD, particularly in children, is a controversial subject. Current treatment includes therapy or medication, or a combination of both. In fact, studies show that medication by itself, without some kind of therapy, is not likely to improve a child's outcome in the long-term. Family therapy, behavioral therapy, social skills training, and parent skills training are often used. Many parents investigate nutritional therapies (such as elimination diets or high-dose vitamins), but so far there is no clear evidence that they are effective. Preliminary evidence indicates that homeopathy and mind-body techniques, especially biofeedback, may help improve behavior in children with ADHD.
Lifestyle
Parent skills training offered by skilled clinicians provides parents with tools and techniques for managing their child's behavior. Behavior therapy rewards appropriate behavior and discourages destructive behavior. It can be performed by parents and teachers working together with therapists and doctors. For example, older children with ADHD may be rewarded with points or tokens, or even written behavioral contracts with their parents. Creating charts with stars for good behavior may work for younger children. On the other hand, timeouts may discourage undesirable behavior. Other techniques include:
- Setting rules that are easily understood, developmentally appropriate, and not unduly harsh
- Avoiding repeated commands once the child has been reminded of the consequences
- Disciplining the child before becoming too angry and frustrated
- Following discipline with praise when the child follows the rules and behaves appropriately
In addition to behavioral intervention at home, changes in the classroom environment (or work, in the case of adolescents or adults) are significant parts of the treatment plan. Hyperactive children do best in highly structured circumstances with a teacher experienced in handling their disruptive behavior and capable of adapting to their distinctive cognitive style. Interactions with groups are often very challenging for a child with ADHD. Social skills training, appropriate classroom placement, and clear rules of engagement with peers are essential.
Adults with ADHD may benefit from behavioral therapies, including cognitive remediation, couple therapy, and family therapy.
Complementary and Alternative Therapies
According to a recent survey, many parents use complementary and alternative treatments for their children with ADHD, with nutritional therapies being the most common. Although studies show conflicting results, if your child appears sensitive to certain foods, talk to your doctor about eliminating them for a brief period to see if his symptoms improve. Putting a child on any diet should be done only under the supervision of your doctor.
Diets
The Feingold diet was developed in the 1970s by Benjamin Feingold. He believed that artificial colors, flavors, and preservatives, as well as naturally occurring salicylates (chemicals similar to aspirin that are found in many fruits and vegetables), were a major cause of hyperactive behavior and learning disabilities in children. Studies examining the diet's effect have been mixed. Most show no benefit, although there is some evidence that salicylates may play a role in hyperactivity in a small number of children. Because the Feingold diet is difficult to follow and also involves changes in family lifestyle (children are encouraged to participate in creating meals, for example), you should talk with your doctor before trying it.
Other dietary therapies may concentrate on eating foods that are high in protein and complex carbohydrates, and eliminating sugar and artificial sweeteners from the diet. However, studies show no relation between sugar and ADHD. In one study, children whose diets were high in sugar or artificial sweeteners behaved no differently than children whose diets were free of these substances. This was true even among children whose parents described them as having a sensitivity to sugar.
Some doctors who focus on nutrition say they see positive results when testing for food allergies and using an elimination diet. If you think your child might benefit from food allergy testing or an elimination diet, talk to a doctor who has experience in nutrition for children with ADHD.
Vitamins and Minerals
- Magnesium (200 mg per day) -- Symptoms of magnesium deficiency include irritability, decreased attention span, and mental confusion. Some experts believe that children with ADHD may be showing the effects of mild magnesium deficiency. In one preliminary study of 75 magnesium-deficient children with ADHD, those who received magnesium supplements showed an improvement in behavior compared to those who did not receive the supplements.
- Vitamin B6 -- Adequate levels of vitamin B6 are needed for the body to make and use brain chemicals, including serotonin, dopamine, and norepinephrine, the chemicals affected in children with ADHD. One preliminary study found that B6 pyridoxine was slightly more effective than Ritalin in improving behavior among hyperactive children. However, the study used a high dose of B6, which could cause nerve damage (although none occurred in the study). Other studies have shown that B6 has no effect on behavior. Because high doses can be dangerous, do not give your child B6 without your doctor's supervision.
- Zinc (35 mg per day) -- Zinc regulates the activity of brain chemicals, fatty acids, and melatonin, all of which are related behavior. Several studies have found that zinc may help improve behavior, but only slightly. Higher doses of zinc can be dangerous, so talk to your doctor before giving zinc to a child or taking it yourself.
- Essential fatty acids -- Fatty acids, such as those found in fish and fish oil (omega-3 fatty acids) and evening primrose oil (omega-6 fatty acids), are "good fats" that play a key role in normal brain function. Experts have suggested them as a treatment for ADHD. The results of studies are mixed, but research continues. Omega-3 fatty acids are also good for heart health in adults, but high doses may increase the risk of bleeding. If you want to try fish oil to see if it reduces ADHD symptoms in you or your child, talk to your doctor about the best dose.
- L-carnitine -- L-carnitine is formed from an amino acid and helps cells in the body produce energy. One study found that 54% of a group of boys with ADHD showed improvement in behavior when taking L-carnitine, but more research is needed to confirm any benefit. Because L-carnitine has not been studied for safety in children, talk to your doctor before giving a child L-carnitine.
Herbs
Herbs are generally a safe way to strengthen and tone the body's systems. As with any therapy, you should work with your health care provider to get your problem diagnosed before starting any treatment. You may use herbs as dried extracts (capsules, powders, teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, you should make teas with 1 tsp. herb per cup of hot water. Steep covered 5 - 10 minutes for leaf or flowers, and 10 - 20 minutes for roots. Drink 2 - 4 cups per day. You may use tinctures alone or in combination as noted.
Several herbal remedies for ADHD are sold in the United States and Europe. But few scientific studies have been done to see whether these herbs improve symptoms of ADHD. One or more of the following calming herbs may be recommended for people with ADHD:
- Roman chamomile (Chamaemelum nobile)
- Valerian (Valerian officinalis)
- Lemon balm (Melissa officinalis)
- Passionflower (Passiflora incarnata)
Other herbs commonly contained in botanical remedies for ADHD include:
- Gingko (Gingko biloba) -- used to improve memory and mental sharpness.
- American ginseng (Panax quinquefolium ) and gingko -- One study suggests that gingko in combination with ginseng may improve symptoms of ADHD.
Massage
Relaxation techniques and massage can reduce anxiety and activity levels in children and teens. In one study, teenage boys with ADHD who received 15 minutes of massage for 10 consecutive school days showed significant improvement in behavior and concentration compared to those who were guided in progressive muscle relaxation for the same duration of time.
Homeopathy
Before prescribing a remedy, homeopaths take into account a person's constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
In a study of 43 children with ADHD, those who received an individualized homeopathic remedy showed a significant improvement in behavior compared to children who received placebo. The homeopathic remedies found to be most effective included:
- Stramonium -- for children who are fearful, especially at night
- Cina -- for children who are irritable and dislike being touched; whose behavior is physical and aggressive
- Hyoscyamus niger -- for children who have poor impulse control, talk excessively or act overly exuberant
Biofeedback
Mind-body techniques such as hypnotherapy, progressive relaxation, and biofeedback may be useful in treating children and teens. Through these techniques, children are often able to learn coping skills they can use for the rest of their lives. These treatments allow children to gain a sense of control and mastery, increase self-esteem, and decrease stress.
Biofeedback operates on the principle that children can be trained to modify brain activity associated with ADHD and increase brain activity associated with attention. Several studies have shown positive results.
Other Considerations
Prognosis and Complications
As many as half of all children with ADHD who receive appropriate treatment learn to control symptoms and function well as adults. Research suggests that children who receive treatment that combines therapies such as medication, behavioral therapy, and biofeedback are less likely to have behavioral problems as they grow up. In most cases, ADHD can be effectively managed throughout life.
Autism
Autism is one of a group of complex developmental disorders (autism spectrum disorders) that appears in the first 3 years of life, although it is sometimes diagnosed much later. Children with autism have trouble with social and communication skills -- most commonly, social interactions, language, and behavior (including restricted and repetitive patterns of behavior). Researchers don’t know what causes autism. Although there has been a lot of press about whether vaccines can trigger autism, a number of studies have found no link between autism and vaccines. Autism has no cure, but early and aggressive intervention may help parents and children learn to manage symptoms and improve their quality of life.
Signs and Symptoms
The symptoms may vary from moderate to severe.
Each child’s behavior is unique, but here are some common signs in the three areas most likely to be affected -- language, social interaction, and behavior:
Communication:
- Can’t start or sustain a social conversation
- Develops language slowly or not at all
- Repeats words or memorized passages, like commercials, but doesn’t understand them
- Doesn’t refer to self correctly (for example, says "you want water" when the child means "I want water")
- Uses nonsense rhyming
- Uses gestures instead of words
Social interaction:
- Doesn’t seem aware of others’ feelings
- Is withdrawn
- Prefers to spend time alone, rather than with others
- May not respond to eye contact or smiles
- May avoid eye contact
- Doesn’t like to be held
- Doesn’t respond to his name
Behavior:
- Uses repetitive body movements
- May find normal noises painful and hold hands over ears
- May be sensitive to light
- May find even slight touch to be overstimulating
- Rubs surfaces, mouths or licks objects
- Doesn’t like even the smallest changes in routine; needs everything to be the same
- "Acts up" with intense tantrums
Causes
Researchers don’t know what causes autism, and it’s likely that there may be several causes. Genetic factors seem to be important, and research shows that a number of genes may be involved.
Many other possible causes have been suspected, but not proven. Some researchers believe that damage to a specific part of the brain (the amygdala) may be involved. Other researchers are looking at whether a virus may trigger symptoms.
Some parents have heard that the Measles, Mumps, and Rubella (MMR) vaccine that children receive may cause autism. Several major studies have found no connection between the vaccine and autism. The American Academy of Pediatrics and the Centers for Disease Control and Prevention report that there is no proven link between autism and the MMR vaccine.
Some doctors think the increase in the number of children with autism is due to better diagnosis and newer definitions of autism. The term “autism spectrum disorders” now includes a wider range of developmental problems.
Risk Factors
Autism is four times more likely to develop in boys than in girls, and it may be inherited. In fact, about 50% of all boys with autism have a parent with the disease.
Autism occurs more frequently in children with rare genetic disorders and other medical conditions, such as tuberous sclerosis, phenylketonuria, neurofibromatosis, and epilepsy.
Some research suggests that children born to older fathers (over age 40) may be more likely to develop autism.
Diagnosis
There is no specific test to diagnose autism. Children develop at different rates, and your pediatrician will look at your child’s development during regular check-ups. Your child may need further evaluation if he or she:
- Isn’t babbling by 12 months
- Doesn’t gesture (pointing, waving bye-bye) by 12 months
- Isn’t saying single words by 16 months
- Doesn’t say two-word spontaneous phrases by 24 months (not just echoing)
- Loses any language or social skills at any age
Children with known or suspected autism will often have genetic testing (looking for chromosome abnormalities) and perhaps metabolic testing.
Treatment Approach
Children with autism do best with an early, intensive, appropriate treatment program. An experienced specialist or team should design an individual program specifically for your child. A number of effective therapies are available. The best treatment plan may use a combination of techniques.
Teaching Programs
There are many types of educational programs for children with autism. Many children do well with very structured programs that reinforce the learning and practice of certain skills. When started early (pre-school) these programs may help a child advance in development and learn to function well.
Medications
Medicines are often used to treat behavior or emotional problems that people with autism may have. These include hyperactivity, impulsiveness, attention problems, irritability, mood swings, outbursts, tantrums, aggression, sleep problems, and anxiety.
Treatment Options
Diet
Some children with autism seem to respond to a gluten-free or a casein-free diet. Gluten is found in foods containing wheat, rye, and barley. Casein is found in milk, cheese, and other dairy products. Not all experts agree that dietary changes will make a difference, and a review of studies in 2008 found no evidence that the diets helped. However, some parents say they do see a difference in their children’s behavior. If you want to try a special diet, talk to a registered dietitian who has experience working with children with autism.
Some studies have suggested that vitamin B6 and vitamin C may help some children with autism. The studies examining whether vitamin B6 may help used doses that are higher than the recommended amount (enough to be potentially toxic) and should not be given except under a doctor’s supervision. Some doctors suggest adding magnesium to vitamin B6 because the combination may have better results, although two studies did not find any benefit.
One small study found that vitamin C supplements may help improve behavior in children with autism. The amounts used were high enough to possibly cause diarrhea. More research is needed on vitamin C and autism.
If you are considering these supplements, it is important to talk with your doctor, a gastroenterologist (doctor who specializes in the digestive system), and a registered dietitian. You want to be sure that your child is still receiving enough calories, nutrients, and a balanced diet, and is not taking too much of a supplement.
Touch Therapy and Massage
Research shows that some children with autism have fewer symptoms after several weeks of touch therapy. In one clinical study, after 16 weeks of massage therapy for their children, parents said they felt physically and emotionally closer to their children and the children gave a range of cues to initiate massage at home.
Several clinical studies have found that children who had Qigong massage (a type of massage that focuses on energy) showed an improvement in behavior and an increase in language development, as well as improvement in motor skills, sensory function, and general health.
Art, Music, and Pet Therapy
Art therapy, music therapy, animal therapy, and sensory integration therapy provide opportunities for children who have autism to develop social and communication skills.
Art therapy offers a child a nonverbal way to express his or her feelings.
Music therapy including singing helps develop speech and language skills. In fact, research shows that any music therapy may reduce symptoms for children and adolescents with autism.
Animal therapy may include therapeutic horse riding programs and swimming with dolphins. These types of therapies can help improve motor skills, while also building self-confidence. Some studies suggest that children who interact with dolphins learn faster and retain more information than children who learned in a classroom setting.
Sensory integration focuses on helping children reorganize and integrate what they perceive with their senses so they can better understand the outside world.
While there is little scientific evidence supporting these therapies, many parents and therapists say their child’s behavior and communication skills improve, and that the children seem to enjoy these therapies.
Prognosis/Possible Complications
Autism is a challenging condition for children and their families, but the outlook is much better than it was a generation ago. Today, doctors and therapists can help reduce many of the symptoms of autism, though most people will be affected on some level throughout their lives.
Autism can be associated with other disorders that affect the brain, such as mental retardation or fragile X syndrome. Some people with autism will develop seizures.
Many families find a support group helps them cope with the challenges of autism.
Following Up
You will need a team of educational and medical professionals to help treat a child with autism. It is important to find teachers, doctors, and behavioral specialists who can help you navigate the medical and educational landscape (including what legal and financial options exist for schooling and treating children with disabilities).
Other Considerations
Viral infection during the first three months of pregnancy -- particularly with rubella -- is a suspected cause of autism.